{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:37:53Z","timestamp":1788280673675,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2006,8,25]],"date-time":"2006-08-25T00:00:00Z","timestamp":1156464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:p><jats:bold>Objectives\u2002<\/jats:bold> To compare the cost effectiveness of laparoscopic versus open colposuspension for the treatment of female urinary stress incontinence.<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> Cost utility analysis alongside a randomised controlled trial.<\/jats:p><jats:p><jats:bold>Setting\u2002<\/jats:bold> Six gynaecological surgical centres within the UK.<\/jats:p><jats:p><jats:bold>Population\/Sample\u2002<\/jats:bold> Women with proven stress urinary incontinence requiring surgery.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Open abdominal retropubic colposuspension or laparoscopic colposuspension carried out by experienced surgeons.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Cost, measured in pounds sterling and generic health\u2010related quality of life, measured using the EQ\u20105D. The latter was used to estimate patient\u2010specific quality\u2010adjusted life years (QALYs).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Healthcare resource use over 6\u2010month follow up translated into costs of \u00a31805 for the laparoscopic arm and \u00a31433 for the open arm (differential mean cost \u00a3372; 95% credibility interval [CrI]: 274\u2013471). At 6 months, QALYs were slightly higher in the laparoscopic arm relative to the open arm (0.005; 95% CrI: \u22120.012 to 0.023). Therefore, the cost of each extra QALY in the laparoscopic group (the incremental cost\u2010effectiveness ratio [ICER]) was \u00a374,400 at 6 months. At 24 months, the laparoscopic arm again had a higher mean QALY score compared to the open surgery group. Thus, assuming that beyond 6 months the laparoscopic colposuspension would not lead to any significant additional costs compared with open colposuspension, the ICER was reduced to \u00a39300 at 24 months. Extensive sensitivity analyses were carried out to test assumptions made in the base case scenario.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Laparoscopic colposuspension is not cost effective when compared with open colposuspension during the first 6 months following surgery, but it may be cost effective over 24 months.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2006.01036.x","type":"journal-article","created":{"date-parts":[[2006,8,25]],"date-time":"2006-08-25T23:32:12Z","timestamp":1156548732000},"page":"1014-1022","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Cost\u2010effectiveness analysis of open colposuspension versus laparoscopic colposuspension in the treatment of urodynamic stress incontinence"],"prefix":"10.1111","volume":"113","author":[{"given":"JC","family":"Dumville","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Manca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HC","family":"Kitchener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ARB","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DJ","family":"Torgerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,8,25]]},"reference":[{"key":"e_1_2_9_2_2","article-title":"Smith ARB on behalf of the COLPO study group. 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