{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:42:59Z","timestamp":1761154979870},"reference-count":5,"publisher":"Wiley","issue":"s3","license":[{"start":{"date-parts":[[2006,12,19]],"date-time":"2006-12-19T00:00:00Z","timestamp":1166486400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>Preterm birth is never low risk and there are advantages gained by prolonging gestation even at relatively advanced stages of pregnancy. This means that high\u2010value treatments should not just be reserved for high\u2010risk pregnancies. Some women treated with tocolytics will experience adverse events, and some adverse events are particularly associated with different classes of tocolytic agents. Cardiovascular adverse events are particularly common with beta\u2010agonists and there have been several maternal deaths from pulmonary oedema as a result of beta\u2010agonist use for tocolysis. Calcium channel blockers are often associated with maternal hypotension, and a number of case studies reporting serious adverse events have been reported. The aim of this case study is to discuss what can be done if a patient experiences adverse events with tocolytics, and suggests approaches to continuing patient management and implications for obstetric practice.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2006.01138.x","type":"journal-article","created":{"date-parts":[[2006,12,21]],"date-time":"2006-12-21T02:24:33Z","timestamp":1166667873000},"page":"116-117","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["\u2018Normal\u2019 pregnancy with adverse events on initial tocolytic treatment"],"prefix":"10.1111","volume":"113","author":[{"given":"J","family":"Dudenhausen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,19]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(98)00052-8"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.4.659"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.052407"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13259.x"},{"key":"e_1_2_2_6_2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1471-0528.2001.00043.x","article-title":"Effectiveness and safety of the oxytocin antagonist atosiban versus beta\u2010adrenergic agonists in the treatment of preterm labour","volume":"108","author":"The Worldwide Atosiban versus Beta\u2010agonists Study Group","year":"2001","journal-title":"BJOG"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1471-0528.2006.01138.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1471-0528.2006.01138.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T21:17:45Z","timestamp":1694639865000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1471-0528.2006.01138.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":5,"journal-issue":{"issue":"s3","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1111\/j.1471-0528.2006.01138.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1471-0528.2006.01138.x","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]},"assertion":[{"value":"2006-12-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}