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Immunological function of the cervix and mucus plug is thought to be important in minimising the ingress of microbes, which can lead to chorioamnionitis and rupture of the amniotic membranes. In this review, we examine the background of traditional cervical cerclage and introduce the concept of the occlusion suture and its potential benefit in reducing the risk of recurrent preterm prelabour rupture of membranes.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2006.01247.x","type":"journal-article","created":{"date-parts":[[2007,4,26]],"date-time":"2007-04-26T07:38:52Z","timestamp":1177573132000},"page":"532-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Could a cervical occlusion suture be effective at improving perinatal outcome?"],"prefix":"10.1111","volume":"114","author":[{"given":"M","family":"Noori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RB","family":"Helmig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PJ","family":"Steer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.137"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(50)90342-5"},{"key":"e_1_2_6_4_2","first-page":"299","article-title":"A new method of operative treatment for habitual abortion in the second trimester of pregnancy","volume":"52","author":"Shirodkar VH","year":"1955","journal-title":"Antiseptic"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1957.tb02650.x"},{"key":"e_1_2_6_6_2","first-page":"145","article-title":"Transabdominal cervicouterine cerclage during pregnancy for the treatment of cervical incompetency","volume":"25","author":"Benson RC","year":"1965","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.108837"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1984.tb04841.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1984.tb04840.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb15300.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200206000-00023"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200204000-00014"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.124289"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.114854"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106851"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.118163"},{"issue":"20","key":"e_1_2_6_17_2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1046\/j.1471-0528.2003.00033.x","article-title":"Fetal fibronectin \u2013 how useful is it in the prediction of preterm birth?","volume":"110","author":"Leitich H","year":"2003","journal-title":"BJOG"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106766"},{"issue":"20","key":"e_1_2_6_19_2","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1046\/j.1471-0528.2003.00062.x","article-title":"Role of cytokines and other inflammatory mediators","volume":"110","author":"Winkler M","year":"2003","journal-title":"BJOG"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106556"},{"issue":"20","key":"e_1_2_6_21_2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1471-0528.2003.00034.x","article-title":"Infection in the prediction and antibiotics in the prevention of spontaneous preterm labour and preterm birth","volume":"110","author":"Lamont RF","year":"2003","journal-title":"BJOG"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.339"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12823-1"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.167"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198810133191503"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.116685"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00525.x"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123034"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123937"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01250.x"},{"key":"e_1_2_6_31_2","first-page":"406","article-title":"Prevention of prematurity. 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