{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:29:53Z","timestamp":1783639793692,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,5,16]],"date-time":"2007-05-16T00:00:00Z","timestamp":1179273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p><jats:bold>Objective\u2002<\/jats:bold> To compare two postpartum laxative regimens in women who have undergone primary repair of obstetric anal sphincter injury.<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> Randomised controlled trial.<\/jats:p><jats:p><jats:bold>Setting\u2002<\/jats:bold> National Maternity Hospital, Dublin.<\/jats:p><jats:p><jats:bold>Population\u2002<\/jats:bold> A total of 147 postpartum women who had sustained anal sphincter injury at vaginal birth.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Women were randomised to receive either lactulose alone thrice daily for the first three postpartum days followed by sufficient lactulose to maintain a soft stool over the following 10 days (lactulose group, <jats:italic>n<\/jats:italic>= 77) or the lactulose regimen combined with a sachet of ispaghula husk daily for the first 10 postpartum days (Fybogel\u2122 group, <jats:italic>n<\/jats:italic>= 70). All patients kept a diary of bowel habit for the first 10 postpartum days and were invited to return for review at 3 months postpartum.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Patient discomfort with first postpartum bowel motion, incidence of postnatal constipation and incontinence and incontinence score in postnatal period.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Pain scores were similar in the two treatment groups; but incontinence in the immediate postnatal period was more frequent with the two preparations compared with lactulose alone (32.86% versus 18.18%, <jats:italic>P<\/jats:italic>= 0.03).<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> This study does not support routine prescribing of a stool\u2010bulking agent in addition to a laxative in the immediate postnatal period for women who have sustained anal sphincter injury at vaginal delivery.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2007.01331.x","type":"journal-article","created":{"date-parts":[[2007,5,16]],"date-time":"2007-05-16T16:56:37Z","timestamp":1179334597000},"page":"736-740","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Randomised clinical trial of a laxative alone versus a laxative and a bulking agent after primary repair of obstetric anal sphincter injury"],"prefix":"10.1111","volume":"114","author":[{"given":"M","family":"Eogan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Daly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Behan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PR","family":"O\u2019Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"O\u2019Herlihy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,5,16]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6933.887"},{"key":"e_1_2_7_3_2","volume-title":"Management of third and fourth degree perineal tears following vaginal delivery","author":"Royal College of Obstetricians and Gynaecologists","year":"2001"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002866.pub2"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-2-9"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/01443610410001645433"},{"key":"e_1_2_7_7_2","article-title":"Antibiotic prophylaxis for fourth\u2010degree perineal tear during vaginal birth","author":"Buppasiri P","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0009-6"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00119-1"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.10.797"},{"key":"e_1_2_7_12_2","first-page":"563","article-title":"Can women with intrapartum rupture of the anal sphincter still suffer two decades later?","volume":"104","author":"Haadem K","year":"1997","journal-title":"Acta Obstet Gynecol Scand"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1471-0528.2007.01331.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1471-0528.2007.01331.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T13:03:24Z","timestamp":1697029404000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1471-0528.2007.01331.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,16]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1111\/j.1471-0528.2007.01331.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1471-0528.2007.01331.x","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,16]]},"assertion":[{"value":"2007-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}