{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:14:00Z","timestamp":1782972840763,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,12,12]],"date-time":"2008-12-12T00:00:00Z","timestamp":1229040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p><jats:bold>Objectives\u2002<\/jats:bold> To evaluate the effectiveness and tolerance of H Pipelle compared with the standard Pipelle as an endometrial biopsy device at outpatient \u2018no\u2010touch\u2019 hysteroscopy.<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> A prospective randomised trial carried out in an outpatient diagnostic hysteroscopy clinic.<\/jats:p><jats:p><jats:bold>Setting\u2002<\/jats:bold> A large undergraduate teaching hospital.<\/jats:p><jats:p><jats:bold>Population\u2002<\/jats:bold> Sixty women investigated for abnormal menstruation in an outpatient diagnostic hysteroscopy clinic.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Prospective randomised trial comparing the H Pipelle with the standard Pipelle de Cornier.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Adequacy of the biopsy specimens and women\u2019s experience.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Ninety\u2010three percent (H Pipelle) and 87% (Pipelle) of the biopsy specimens were judged to be adequate for histological diagnosis (<jats:italic>P <\/jats:italic>&gt; 0.05). However, obtaining endometrial sampling with the H Pipelle was significantly quicker (median times: 39 seconds [H Pipelle] and 102 seconds [Pipelle], <jats:italic>P <\/jats:italic>&lt; 0.0001) and less painful (median visual analogue scale score: 1 [H Pipelle] and 5 [Pipelle], <jats:italic>P <\/jats:italic>= 0.011).<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The H Pipelle not only makes it possible to perform hysteroscopy and endometrial biopsy with minimal instrumentation but is also associated with a shorter biopsy time and less discomfort than the standard Pipelle without any loss of biopsy adequacy.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2008.01992.x","type":"journal-article","created":{"date-parts":[[2008,12,12]],"date-time":"2008-12-12T12:25:16Z","timestamp":1229084716000},"page":"32-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["A randomised trial comparing the H Pipelle with the standard Pipelle for endometrial sampling at \u2018no\u2010touch\u2019 (vaginoscopic) hysteroscopy"],"prefix":"10.1111","volume":"116","author":[{"given":"S","family":"Madari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Al\u2010Shabibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Papalampros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Papadimitriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Magos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,12,12]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00108-1"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.06.004"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(97)80019-9"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(03)00546-6"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del298"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(00)00528-5"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2006.03.010"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200210000-00023"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.11.026"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00425.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2007.00699.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1990.tb02458.x"},{"key":"e_1_2_7_14_2","first-page":"427","article-title":"Comparison of endometrial biopsy with the endometrial Pipelle and Vabra aspirator","volume":"33","author":"Kaunitz AM","year":"1988","journal-title":"J Reprod Med"},{"key":"e_1_2_7_15_2","first-page":"786","article-title":"Evaluation of the Pipelle curette for endometrial biopsy","volume":"34","author":"Henig I","year":"1989","journal-title":"J Reprod Med"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(12)90744-9"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200208000-00004"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1471-0528.2008.01992.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1471-0528.2008.01992.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T21:40:41Z","timestamp":1697406041000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1471-0528.2008.01992.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,12]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.1111\/j.1471-0528.2008.01992.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1471-0528.2008.01992.x","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,12]]},"assertion":[{"value":"2008-12-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}