{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:59:18Z","timestamp":1759564758926},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T00:00:00Z","timestamp":1264464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p> <jats:italic>Please cite this paper as:<\/jats:italic> Patel A, Thampy N, Hemming D, Naik R. A clinical review of borderline glandular cells reported on liquid\u2010based cervical cytology. BJOG 2010;117:1051\u20131059.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To review the clinical outcome of women presenting with borderline glandular cells on liquid\u2010based cervical cytology (LBC).<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> Retrospective review.<\/jats:p><jats:p><jats:bold>Population and setting\u2002<\/jats:bold> Women seen at a colposcopy clinic over a 26\u2010month period referred with borderline glandular cells on LBC.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Review of the case notes and cytology, pathology and colposcopy databases of all women referred with borderline glandular cells on LBC between June 2006 and August 2008.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Final histological diagnosis.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Sixty\u2010nine women were identified (0.19% of all smears). Twenty\u2010seven women (39.1%) had premalignant or malignant lesions, five (7.2%) had cancers and 22 (31.9%) had intraepithelial neoplasia, 19 (27.5%) of which were cervical squamous intraepithelial neoplasia (CIN) and three (4.3%) of which were cervical glandular intraepithelial neoplasia (CGIN). No women under 35\u2003years of age with normal and satisfactory colposcopy had premalignant or malignant lesions. Despite normal and satisfactory colposcopy, three women over 35\u2003years had significant lesions: one high\u2010grade CIN, one CGIN and one squamous cell carcinoma.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> On the basis of our results, it would be considered acceptable to manage women under 35\u2003years of age with normal and satisfactory colposcopy conservatively. In women above 35\u2003years of age, we would recommend a diagnostic \u2018large loop excision of the transformation zone\u2019 procedure, irrespective of the colposcopic findings.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2009.02477.x","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T10:24:16Z","timestamp":1264501456000},"page":"1051-1059","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A clinical review of borderline glandular cells reported on liquid\u2010based cervical cytology"],"prefix":"10.1111","volume":"117","author":[{"given":"A","family":"Patel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Thampy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Hemming","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Naik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,7,6]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2004.00177.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.47.6.481"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.39.9.933"},{"key":"e_1_2_5_5_2","volume-title":"Achievable Standards, Benchmarks for Reporting and Criteria for Evaluating Cervical Cytopathology","author":"NHS Cervical Screening Programme","year":"2000"},{"key":"e_1_2_5_6_2","volume-title":"NHSCSP Cervical Pathology Atlas","author":"NHS Cervical Screening Programme","year":"2006"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00585.x"},{"key":"e_1_2_5_8_2","volume-title":"Colposcopy and Programme Management: Guidelines for the NHS Cervical Screening Programme","author":"NHS Cervical Screening Programme","year":"2004"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000202401.29145.68"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13300.x"},{"key":"e_1_2_5_11_2","volume-title":"Evaluation of HPV\/LBC: Cervical Screening Pilot Studies. 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