{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:14:20Z","timestamp":1791465260399,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,10,21]],"date-time":"2011-10-21T00:00:00Z","timestamp":1319155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:italic>Please cite this paper as:<\/jats:italic> Kuleva M, Khen\u2010Dunlop N, Dumez Y, Ville Y, Salomon L. Is complex gastroschisis predictable by prenatal ultrasound? BJOG 2012;119:102\u2013109.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To establish a correlation between prenatal ultrasound findings and postnatal outcome in neonates with gastroschisis (GS).<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> Retrospective case\u2013control study.<\/jats:p><jats:p><jats:bold>Setting\u2002<\/jats:bold> Prenatal ultrasound reports, labour and neonatal intensive care unit notes, and paediatric surgical clinic records were reviewed.<\/jats:p><jats:p><jats:bold>Population\u2002<\/jats:bold> Neonates with an antenatal diagnosis of isolated GS.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> The neonates were divided into two groups: one with associated bowel complications including intestinal atresia, perforation, necrosis or volvulus (\u2018complex\u2019 GS), and the second without bowel complication (\u2018simple\u2019 GS). Prenatal ultrasound markers: small\u2010for\u2010gestational\u2010age, intra\u2010abdominal and extra\u2010abdominal bowel dilatation (&gt;6\u2003mm), thickened intestinal wall and stomach dilatation were correlated with outcome.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Fetal or neonatal death in complex versus simple GS. Time on parenteral nutrition and duration of hospital stay were also noted.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> In all, 105 cases were eligible for analysis. Survival rate was 101\/105 (96.2%). None of the ultrasound markers was predictive of fetal or neonatal death. Fourteen of 103 live\u2010born babies (14.6%) had complex GS, which was associated with longer time on parenteral nutrition [8.0 (51.5\u2013390) versus 33.5 (25.3\u201353.3) days, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001] and longer duration of hospital stay [85.3 (55.5\u2013210) versus 41.5 (33.0\u201364.8) days, <jats:italic>P\u2003<\/jats:italic>&lt;\u20030.001]. Infants with complex GS were more likely to require bowel resection and stoma placement (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.05). Intra\u2010abdominal bowel dilatation was the only predictive ultrasound marker of complex GS (odds ratio 4.13, 95% CI 1.32\u201312.90; <jats:italic>P\u2003<\/jats:italic>=\u20030.018). Receiver operating characteristic curve for observed\/expected bowel diameter yielded 6 as the cutoff value for predicting complex GS (odds ratio 7.9, 95% CI 2.3\u201327.3; <jats:italic>P\u2003<\/jats:italic>=\u20030.001) with 54% and 88% for sensibility and specificity, respectively.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Intra\u2010abdominal bowel dilatation is the only ultrasound marker predictive of complex GS but it is a strong marker.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2011.03183.x","type":"journal-article","created":{"date-parts":[[2011,10,21]],"date-time":"2011-10-21T12:44:58Z","timestamp":1319201098000},"page":"102-109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["Is complex gastroschisis predictable by prenatal 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