{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:26:16Z","timestamp":1783470376226,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T00:00:00Z","timestamp":1323734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:italic>Please cite this paper as:<\/jats:italic> Saso S, Ghaem\u2010Maghami S, Chatterjee J, Naji O, Farthing A, Mason P, McIndoe A, Hird V, Ungar L, Del Priore G, Smith J. Abdominal radical trachelectomy in West London. BJOG 2012;119:187\u2013193.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> Traditionally, the surgical management of invasive cervical carcinoma that has progressed beyond microinvasion has been a radical abdominal hysterectomy. However, this results in the loss of fertility, with significant consequences for the young patient. This report describes abdominal radical trachelectomy (ART) as a potential replacement for radical hysterectomy in patients with stage IA2\u2013IIA cervical cancer who desire a fertility\u2010sparing procedure without decreasing the curative rates.<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> Observational, retrospective study.<\/jats:p><jats:p><jats:bold>Setting\u2002<\/jats:bold> Teaching hospital and regional cancer centre in London, UK.<\/jats:p><jats:p><jats:bold>Population\u2002<\/jats:bold> Patients undergoing ART.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Patients presenting during the period 2000\u20132009 with cervical cancer stage IA2\u2013IIA were offered a trachelectomy, if they expressed a desire to preserve fertility. The type of trachelectomy (vaginal\/abdominal) was chosen based on patient anatomy and neoplastic and magnetic resonance imaging characteristics. Each patient was counselled as to the experimental nature of the procedure.<\/jats:p><jats:p><jats:bold>Main outcome measures\u2002<\/jats:bold> Survival, recurrence and fertility issues among ART patients.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> A total of 30 patients underwent ART (open and laparoscopic) between 2001 and 2009. Three patients presented with a recurrence, two of which have died (median follow\u2010up: 24\u2003months). Only three patients required further surgical re\u2010intervention because of operative complications. Ten patients attempted to conceive, resulting in three conceptions (30%) and two live children.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Abdominal radical trachelectomy provides a feasible, cost\u2010effective and safe treatment option for young women who have been diagnosed with early\u2010stage cervical cancer and wish to preserve their fertility.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2011.03213.x","type":"journal-article","created":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T18:15:41Z","timestamp":1323800141000},"page":"187-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Abdominal radical trachelectomy in West London"],"prefix":"10.1111","volume":"119","author":[{"given":"S","family":"Saso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Ghaem\u2010Maghami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Naji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Farthing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Mason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"McIndoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Hird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Ungar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Del Priore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JR","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,13]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"53","article-title":"Exploring a cancer patient\u2019s reproductive options","volume":"1","author":"Del Priore G","year":"2002","journal-title":"Contemp Ob\/Gyn"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/29.2.197"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.77.4.495"},{"key":"e_1_2_6_5_2","first-page":"285","article-title":"La trachelectomie elargie (TE) une alternative a l\u2019hysterectomie radicale dans le traitement des cancers infiltrants developes sur la face externe du col uterin","volume":"2","author":"Dargent D","year":"1994","journal-title":"J d\u2019Obstetrique et Gynecol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2000.5912"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(89)90143-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.07.020"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19991201)86:11<2273::AID-CNCR15>3.0.CO;2-C"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.04.027"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb10946.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00421.x"},{"key":"e_1_2_6_13_2","first-page":"93","volume-title":"An Atlas of Gynecologic Oncology, Investigation and Surgery","author":"Boyle DCM","year":"2001"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70084-X"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6158"},{"key":"e_1_2_6_16_2","article-title":"Complications after fertility\u2010preserving radical trachelectomy","volume":"85","author":"Del P","year":"2006","journal-title":"Fertil Steril"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2009.06.036"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.01.032"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000415)88:8<1877::AID-CNCR17>3.0.CO;2-W"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(02)00142-7"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.07.028"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000216015.15415.5f"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01252.x"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; 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