{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:59:59Z","timestamp":1787014799583,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,8,8]],"date-time":"2011-08-08T00:00:00Z","timestamp":1312761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurochemistry"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      <jats:italic>J. Neurochem.<\/jats:italic>\n                      (2011)\n                      <jats:bold>118<\/jats:bold>\n                      , 999\u20131007.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Retina and anterior neural fold homeobox<\/jats:italic>\n                      (\n                      <jats:italic>Rax<\/jats:italic>\n                      ) gene encodes a transcription factor essential for vertebrate eye development. Recent microarray studies indicate that\n                      <jats:italic>Rax<\/jats:italic>\n                      is expressed in the adult rat pineal gland and retina. The present study reveals that\n                      <jats:italic>Rax<\/jats:italic>\n                      expression levels in the rat change significantly during retinal development with a peak occurring at embryonic day 18, whereas\n                      <jats:italic>Rax<\/jats:italic>\n                      expression in the pineal is relatively delayed and not detectable until embryonic day 20. In both tissues,\n                      <jats:italic>Rax<\/jats:italic>\n                      is expressed throughout postnatal development into adulthood. In the mature rat pineal gland, the abundance of Rax transcripts increases 2\u2010fold during the light period with a peak occurring at dusk. These findings are consistent with the evidence that\n                      <jats:italic>Rax<\/jats:italic>\n                      is of functional importance in eye development and suggest a role of\n                      <jats:italic>Rax<\/jats:italic>\n                      in the developing pineal gland. In addition, it would appear possible that\n                      <jats:italic>Rax<\/jats:italic>\n                      contributes to phenotype maintenance in the mature retina and pineal gland and may facilitate 24\u2010h changes in the pineal transcriptome.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1471-4159.2011.07385.x","type":"journal-article","created":{"date-parts":[[2011,7,12]],"date-time":"2011-07-12T19:08:27Z","timestamp":1310497707000},"page":"999-1007","source":"Crossref","is-referenced-by-count":27,"title":["Rax\u200a: developmental and daily expression patterns in the rat pineal gland and retina"],"prefix":"10.1111","volume":"118","author":[{"given":"Kristian","family":"Rohde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin F.","family":"Rath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199603)205:3<293::AID-AJA9>3.0.CO;2-D"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00325-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(92)91199-O"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.041878tb"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808394200"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00555.x"},{"key":"e_1_2_7_8_1","first-page":"137","article-title":"Time of origin of the rat pineal gland cells. 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