{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:21:41Z","timestamp":1760782901581},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T00:00:00Z","timestamp":1166745600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Axillary hyperhidrosis does not have a low\u2010cost, free of secondary effects, satisfactory treatment. Eccrine hidrocystomas have been successfully treated with topical atropine solution.<\/jats:p><jats:p><jats:bold>Hypothesis\u2002<\/jats:bold> Axillary hyperhidrosis could respond to the topical application of atropine solution.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Ten patients were selected. Eight with mild pure primary axillary hyperhidrosis and two with compensatory sweating after sympacthectomy. One milliliter of a water solution of atropine sulfate at 1% was applied twice a day over the affected area and massaged for 30\u00a0s. Treatment was maintained for 15\u00a0days. The results were rated using a scale from 1 to 10 of satisfaction.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Only 2 of the 10 treated patients responded partially to the topical application of atropine sulfate. No local or systemic secondary effects were observed.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The results of the study demonstrated that focal hyperhidrosis does not improve after the local application of anticholinergic drugs such as atropine sulfate.<\/jats:p>","DOI":"10.1111\/j.1473-2165.2006.00273.x","type":"journal-article","created":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T10:59:14Z","timestamp":1166785154000},"page":"294-296","source":"Crossref","is-referenced-by-count":9,"title":["Topical atropine sulfate for the treatment of axillary hyperhidrosis"],"prefix":"10.1111","volume":"5","author":[{"given":"Ramon","family":"Grimalt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Dom\u00ednguez","family":"Tordera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A","family":"Callejas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(99)00111-1"},{"key":"e_1_2_6_3_2","first-page":"1065","article-title":"Endoscopic thoracic sympathectomy for isolated axillary hyperhidrosis","volume":"127","author":"Gossot D","year":"2000","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02441.x"},{"key":"e_1_2_6_5_2","first-page":"670","article-title":"Efficacy and safety of topical atropine in the treatment of multiple eccrine hidrocystomas","volume":"137","author":"Sanz\u2010Sanchez T","year":"2001","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.4065\/80.5.657"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7753(02)73532-X"},{"key":"e_1_2_6_8_2","first-page":"65","volume-title":"Hiperhidrosis, Diagn\u00f3stico y Tratamientos Actuales","author":"Grimalt R","year":"2004"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2896(02)75165-X"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.02.087"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1473-2165.2006.00273.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1473-2165.2006.00273.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T14:49:41Z","timestamp":1697035781000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1473-2165.2006.00273.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1111\/j.1473-2165.2006.00273.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1473-2165.2006.00273.x","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}