{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:40:31Z","timestamp":1771933231700,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,9,23]],"date-time":"2012-09-23T00:00:00Z","timestamp":1348358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The recently described angiographic <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u20101 <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>yocardial <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>eopardy Score (<jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content>) provides a semi\u2010quantitative estimate of the extent of coronary artery disease (<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>). It is simple to use and applicable to all patients including those with bypass grafts. Our objective was to validate the <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> by evaluating its correlation with myocardial ischaemic burden and its accuracy at predicting a prognostic ischaemic threshold. Seventy\u2010five patients with angina and known or suspected <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> referred for coronary angiography prospectively underwent high\u2010resolution <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content> perfusion imaging. There was good correlation between the <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> and myocardial ischaemic burden: <jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b775, <jats:italic>P<\/jats:italic>&lt;0\u00b70001. Area under the <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content> curve for <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> to detect \u226512% myocardial ischaemic burden was 0\u00b787 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0\u00b778\u20130\u00b796). <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> \u22656 predicted \u226512% myocardial ischaemic burden with a sensitivity of 68% and a specificity of 91%. The <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> correlates well with myocardial ischaemic burden. A <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> \u22656 predicts the prognostically important ischaemic threshold of 12% with high specificity. These findings demonstrate that the <jats:styled-content style=\"fixed-case\">BCIS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">JS<\/jats:styled-content> has functional relevance and support its utility for classification of <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> burden in clinical trials and in clinical practice.<\/jats:p>","DOI":"10.1111\/j.1475-097x.2012.01167.x","type":"journal-article","created":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T02:41:11Z","timestamp":1348454471000},"page":"101-108","source":"Crossref","is-referenced-by-count":10,"title":["Validation of the <scp>BCIS<\/scp>\u20101 <scp>M<\/scp>yocardial <scp>J<\/scp>eopardy score using cardiac magnetic resonance perfusion imaging"],"prefix":"10.1111","volume":"33","author":[{"given":"Geraint D. 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