{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T12:20:33Z","timestamp":1780575633900,"version":"3.54.1"},"reference-count":45,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,2,11]],"date-time":"2011-02-11T00:00:00Z","timestamp":1297382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective \u2013<\/jats:bold>To describe the common clinical signs, laboratory abnormalities, treatment, and prognosis associated with acute aldicarb toxicosis in dogs.<\/jats:p><jats:p><jats:bold>Design \u2013<\/jats:bold>Retrospective observational study from 2001 to 2009.<\/jats:p><jats:p><jats:bold>Setting \u2013<\/jats:bold>Urban referral hospital.<\/jats:p><jats:p><jats:bold>Animals \u2013<\/jats:bold>Fifteen client\u2010owned dogs.<\/jats:p><jats:p><jats:bold>Interventions \u2013<\/jats:bold>None.<\/jats:p><jats:p><jats:bold>Measurements and Main Results \u2013<\/jats:bold>The most common clinical signs associated with acute aldicarb toxicosis were vomiting, ptyalism, diarrhea, and tremors. Of the 15 dogs, 11 were admitted to the hospital for treatment, 2 were euthanized at presentation and 2 were discharged against medical advice following minimal treatment and lost to follow\u2010up. Laboratory abnormalities included lactic acidosis and hyperglycemia in 12 and 9 patients, respectively. Treatment of hospitalized dogs included induction of emesis with apomorphine (4 dogs), activated charcoal (5), IV fluids (11), atropine (7), methocarbamol (3), diazepam (1), pralidoxime (1) and diphenhydramine (1). Ten of 11 hospitalized dogs survived to discharge; 1 was euthanized following a respiratory arrest after 36 hours of hospitalization. One patient received mechanical ventilation and treatment for pneumonia before discharge from the hospital. The median duration of hospitalization was 22 hours (range 12\u2013168\u2003h).<\/jats:p><jats:p><jats:bold>Conclusions \u2013<\/jats:bold>Acute aldicarb toxicosis carries a good prognosis for survival and hospital discharge with treatment. Supportive care should be considered for at least 18\u201324 hours to monitor for response to therapy and development of respiratory failure.<\/jats:p>","DOI":"10.1111\/j.1476-4431.2011.00613.x","type":"journal-article","created":{"date-parts":[[2011,2,18]],"date-time":"2011-02-18T11:56:29Z","timestamp":1298030189000},"page":"253-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Acute aldicarb toxicity in dogs: 15 cases (2001\u20132009)"],"prefix":"10.1111","volume":"21","author":[{"given":"John D.","family":"Anastasio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire R.","family":"Sharp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,11]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"3","volume-title":"Handbook of Pesticide Toxicology","author":"Baron RL.","year":"1991"},{"issue":"5","key":"e_1_2_7_3_2","first-page":"447","article-title":"Aldicarb poisoning by an illicit rodenticide imported into the United States","volume":"39","author":"Nelson LS","year":"2001","journal-title":"Tres Pasitos"},{"key":"e_1_2_7_4_2","first-page":"961","volume-title":"Poisonings Associated with Illegal Use of Aldicarb as a Rodenticide \u2013 New York City","author":"Centers_for_Disease_Control","year":"1997"},{"key":"e_1_2_7_5_2","first-page":"267","article-title":"The toxicologic effects of the carbamate insecticide aldicarb in mammals","volume":"72","author":"Risher JF","year":"1987","journal-title":"a review"},{"issue":"11","key":"e_1_2_7_6_2","first-page":"23","article-title":"A carbamate insecticide","volume":"102","author":"Baron RL.","year":"1994","journal-title":"a case study of aldicarb"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31817bcedf"},{"key":"e_1_2_7_8_2","volume-title":"Clinical Toxicology","author":"Ford MD.","year":"2001"},{"key":"e_1_2_7_9_2","volume-title":"Principles and Methods of Toxicology","author":"Hayes AW.","year":"2008"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.3.631"},{"issue":"3","key":"e_1_2_7_11_2","first-page":"260","article-title":"Animal poisoning in Europe. 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