{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:39:23Z","timestamp":1787243963247,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,4,5]],"date-time":"2012-04-05T00:00:00Z","timestamp":1333584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Comparative Oncology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>An overall median survival time (MST) and prognostic factors in rabbits with thymomas treated with megavoltage radiation therapy (RT) were determined in this multi\u2010institutional retrospective case analysis. Medical records for 19 rabbits with suspected or confirmed thymomas treated with RT were evaluated for data including signalment, haematological and serum biochemistry abnormalities, presence of pleural effusion, radiation plan, body weight, total radiation dose and institution administering RT. Statistical significance of these factors related to overall survival was assessed. An overall MST for all 19 rabbits was 313 days; exclusion of 3 rabbits that died acutely during the first 14 days of RT yielded a MST of 727 days. The only factor associated with a significantly decreased survival time was having a body weight lower than mean body weight of 1.57 kg. Radiation treatment\u2010associated complications were infrequent and included radiation\u2010induced myocardial failure, radiation pneumonitis and alopecia.<\/jats:p>","DOI":"10.1111\/j.1476-5829.2011.00273.x","type":"journal-article","created":{"date-parts":[[2012,4,5]],"date-time":"2012-04-05T03:42:35Z","timestamp":1333597355000},"page":"82-94","source":"Crossref","is-referenced-by-count":28,"title":["The use of megavoltage radiation therapy in the treatment of thymomas in rabbits: 19 cases"],"prefix":"10.1111","volume":"10","author":[{"given":"K. M.","family":"Andres","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. T.","family":"Siedlecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Hawkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. K.","family":"Morrisey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Quesenberry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. E.","family":"Valli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. A.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199812000-00004"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(194907)2:4<673::AID-CNCR2820020414>3.0.CO;2-J"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00336.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2004.04.005"},{"key":"e_1_2_6_6_2","volume-title":"Tumors in Domestic Animals","author":"Moulton JE.","year":"1990"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1997.tb03492.x"},{"key":"e_1_2_6_8_2","volume-title":"Ferrets, Rabbits, and Rodents","author":"Hillyer E","year":"1997"},{"key":"e_1_2_6_9_2","first-page":"59","article-title":"Surgical removal of a mediastinal mass in a rabbit.","volume":"4","author":"Harcourt\u2010Brown F","year":"2002","journal-title":"Exotic DVM"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"820","DOI":"10.2460\/javma.1995.206.06.820","article-title":"Thymoma in a geriatric rabbit with hypercalcemia and periodic exophthalmos.","volume":"206","author":"Vernau KM","year":"1995","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000224587"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2007.00587.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.8.1186"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.2460\/javma.1998.213.08.1140","article-title":"Removal of a thymoma via median sternotomy in a rabbit with recurrent appendicular neurofibrosarcoma.","volume":"213","author":"Clippinger TL","year":"1998","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2006.02.010"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.saep.2005.06.003"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2004.04082.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.5326\/0420094"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203266"},{"key":"e_1_2_6_20_2","first-page":"72","article-title":"Familial thymoma and translocation t (14;20) (q24;p13).","volume":"37","author":"Deminatti MM","year":"1994","journal-title":"Annals of Genetics"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700292"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2005.tb03704.x"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.36-6-565"},{"key":"e_1_2_6_24_2","volume-title":"Atlas der Roentgen Diagnostik bei Heimtieren.","author":"Rubel G","year":"1991"},{"key":"e_1_2_6_25_2","volume-title":"Textbook of Rabbit Medicine.","author":"Harcourt\u2010Brown F.","year":"2002"},{"key":"e_1_2_6_26_2","volume-title":"The Biology of the Laboratory Rabbit.","author":"Manning PJ","year":"1994"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(85)50034-0"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2002.0187"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2006.10.002"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2006.tb00716.x"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2008.00061.x"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-37-5-489"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(97)50010-6"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2007.09.002"},{"key":"e_1_2_6_35_2","first-page":"867","article-title":"Serum parathyroid hormone\u2010related protein concentration in a dog with a thymoma and persistent hypercalcemia.","volume":"41","author":"Foley P","year":"2000","journal-title":"Canadian Veterinary Journal"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.41-4-429"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R"},{"issue":"11","key":"e_1_2_6_38_2","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1093\/jn\/121.suppl_11.S95","article-title":"Calcium metabolism of rabbits as an etiological factor for urolithiasis.","volume":"121","author":"Kamphues J.","year":"1991","journal-title":"Journal of Nutrition"}],"container-title":["Veterinary and Comparative Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1476-5829.2011.00273.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1476-5829.2011.00273.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T17:06:41Z","timestamp":1713805601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1476-5829.2011.00273.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,5]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1476-5829.2011.00273.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1476-5829.2011.00273.x","archive":["Portico"],"relation":{},"ISSN":["1476-5810","1476-5829"],"issn-type":[{"value":"1476-5810","type":"print"},{"value":"1476-5829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,5]]}}}