{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T05:11:45Z","timestamp":1781154705333,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,10]],"date-time":"2006-02-10T00:00:00Z","timestamp":1139529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold>Abstract: Objectives: <\/jats:bold> Splenic artery aneurysm (SAA) is usually asymptomatic, but can be fatal if it ruptures. Portal hypertensive patients with varix or splenomegaly are sometimes complicated by SAA. However, there have been no large\u2010scale clinical studies regarding whether liver cirrhosis itself is associated with splenic aneurysm regardless of varix or splenomegaly.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> In the present study, we retrospectively analyzed 303 cirrhotic patients examined with arteriography. The diagnosis and characteristics of SAAs were determined, and the relation with splenic artery diameter was evaluated.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Nine patients (2.97%) had 12 complicated SAAs. The aneurysms, which measured 4\u201322\u2003mm in diameter, were all saccular, and occurred commonly in the splenic hilum (50.0%). A correlation was noted between splenic artery diameter and aneurysm diameter (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>=0.706). Aneurysm growth was strongly associated with an increase in diameter of the splenic artery trunk (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>=0.705), which is closely related to arterial flow.<\/jats:p><jats:p><jats:bold>Conclusions: <\/jats:bold> SAA is considered a complication of cirrhosis. The increase in splenic artery diameter may result in SAA enlargement and rupture. Elective procedures should be considered based on the follow\u2010up of main trunk or diameter of the splenic artery in addition to SAA size, a known risk factor of aneurysmal rupture.<\/jats:p>","DOI":"10.1111\/j.1478-3231.2005.01231.x","type":"journal-article","created":{"date-parts":[[2006,2,10]],"date-time":"2006-02-10T15:23:00Z","timestamp":1139584980000},"page":"291-297","source":"Crossref","is-referenced-by-count":19,"title":["The development and clinical features of splenic aneurysm associated with liver 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