{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T09:48:34Z","timestamp":1761126514265},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T00:00:00Z","timestamp":1171843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe, for the first time, two adult patients with primary biliary cirrhosis (PBC) who presented palpable purpuric lesions on the lower extremities and buttocks. Skin biopsy was consistent with Henoch\u2013Schonlein purpura (HSP). One of the patients exhibited renal and gastrointestinal involvement, as well. A favourable outcome was achieved in both the patients (after treatment with prednisolone only in the patient with renal and gastrointestinal manifestations). The possible pathophysiological relationships between PBC and HSP \u2013 particularly on the significance of the IgA antimitochondrial autoantibodies \u2013 are discussed. To the best of our knowledge, these are the first two cases of HSP, which developed in PBC patients. Therefore, this case study suggests that HSP may be rarely involved in the extensive list of immune\u2010mediated diseases associated with PBC.<\/jats:p>","DOI":"10.1111\/j.1478-3231.2006.01402.x","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T13:34:02Z","timestamp":1171892042000},"page":"280-283","source":"Crossref","is-referenced-by-count":14,"title":["Primary biliary cirrhosis and Henoch\u2013Schonlein purpura: report of two cases and review of the literature"],"prefix":"10.1111","volume":"27","author":[{"given":"Nikolaos K.","family":"Gatselis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelos","family":"Stefos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chrisa","family":"Gioti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eirini I.","family":"Rigopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George N.","family":"Dalekos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,19]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330809"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(99)80006-7"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.80.4.380"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00432479"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00387-8"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.11.023"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2006.01.002"},{"key":"e_1_2_4_9_2","first-page":"281","article-title":"Henoch\u2013Schonlein purpura","volume":"61","author":"Madison DL","year":"2002","journal-title":"a possible complication of hepatitis C related cirrhosis"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)70306-2"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)05419-6"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13808-1"},{"key":"e_1_2_4_13_2","first-page":"397","article-title":"Patterns of autoimmunity in primary biliary cirrhosis patients and their families","volume":"97","author":"Watt FE","year":"2004","journal-title":"a population-based cohort study"},{"key":"e_1_2_4_14_2","first-page":"210","article-title":"Primary biliary cirrhosis","volume":"174","author":"Gershwin ME","year":"2000","journal-title":"an orchestrated immune response against epithelial cells"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/jaut.1998.0220"},{"key":"e_1_2_4_16_2","first-page":"23","article-title":"Primary biliary cirrhosis an epithelitis","volume":"26","author":"Tsuneyama K","year":"1997","journal-title":"evidence of abnormal salivary gland immunohistochemistry"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1478-3231.2006.01402.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1478-3231.2006.01402.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T01:04:59Z","timestamp":1697159099000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1478-3231.2006.01402.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,19]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1111\/j.1478-3231.2006.01402.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1478-3231.2006.01402.x","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,19]]}}}