{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:30:38Z","timestamp":1793460638308,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T00:00:00Z","timestamp":1238976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\/Aims: <\/jats:bold> The transjugular intrahepatic portosystemic shunt (TIPS) is technically divided into TIPS through the left branch of the portal vein (TIPS\u2010LBPV) and TIPS through the right branch of the portal vein (TIPS\u2010RBPV). In order to compare their advantages and disadvantages, this randomized, controlled trial was designed to investigate their outcomes in advanced cirrhotic patients.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> Seventy\u2010two patients were randomly placed into TIPS\u2010LBPV (36 patients) and TIPS\u2010RBPV (36 patients, with four failures) groups, and they were prospectively followed for 2 years after TIPS implantation.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> Patients who underwent the two different kinds of TIPS were balanced during recruitment for this study. The incidences of overall encephalopathy and <jats:italic>de novo<\/jats:italic> encephalopathy in the TIPS\u2010LBPV group were significantly lower than that of the TIPS\u2010RBPV group during follow\u2010up (<jats:italic>P<\/jats:italic>=0.036 and 0.012 respectively). The incidences of rebleeding or re\u2010intervention and improvement of ascites were similar between groups (<jats:italic>P<\/jats:italic>&gt;0.05). Patients undergoing TIPS\u2010RBPV required more rehospitalization and incurred more costs than those who underwent TIPS\u2010LBPV (<jats:italic>P<\/jats:italic>=0.030 and 0.039 respectively). There was no significant difference between the two groups in survival based on a survival curve constructed according to the Kaplan\u2013Meier method (<jats:italic>P<\/jats:italic>&gt;0.05).<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> Patients undergoing TIPS\u2010LBPV had a lower incidence of encephalopathy, less rehospitalization and lower costs after TIPS implantation compared with patients undergoing TIPS\u2010RBPV.<\/jats:p>","DOI":"10.1111\/j.1478-3231.2009.02016.x","type":"journal-article","created":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T09:42:46Z","timestamp":1239010966000},"page":"1101-1109","source":"Crossref","is-referenced-by-count":53,"title":["Outcomes of transjugular intrahepatic portosystemic shunt through the left branch vs. the right branch of the portal vein in advanced cirrhosis: a randomized trial"],"prefix":"10.1111","volume":"29","author":[{"given":"Lei","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianli","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wensheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingling","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianchun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,7,2]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"48","article-title":"Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal bleeding in cirrhosis","volume":"27","author":"Merli M","year":"1998","journal-title":"a randomized multicenter trial. Gruppo Italiano Studio TIPS (G. I. S. T.)"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-4-304"},{"key":"e_1_2_7_4_2","first-page":"1444","article-title":"Outcome of 100 patients after transjugular intrahepatic portosystemic shunt for variceal hemorrhage","volume":"92","author":"Sahagun G","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_7_5_2","first-page":"390","article-title":"Transjugular intrahepatic portosystemic shunt (TIPS) versus endoscopic variceal ligation in the prevention of variceal rebleeding in patients with cirrhosis","volume":"48","author":"Pomier\u2010Layrargues G","year":"2001","journal-title":"a randomised trial"},{"key":"e_1_2_7_6_2","first-page":"825","article-title":"Transjugular intrahepatic portosystemic shunt for refractory ascites","volume":"133","author":"Salerno F","year":"2007","journal-title":"a meta-analysis of individual patient data"},{"key":"e_1_2_7_7_2","first-page":"337","article-title":"Transjugular intrahepatic portosystemic shunt","volume":"25","author":"R\u00f6sch J","year":"2001","journal-title":"present status, comparison with endoscopic therapy and shunt surgery, and future prospectives"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.12.009"},{"key":"e_1_2_7_9_2","first-page":"507","article-title":"Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients","volume":"42","author":"Zheng M","year":"2008","journal-title":"meta-analysis update"},{"key":"e_1_2_7_10_2","first-page":"1282","article-title":"Uncovered transjugular intrahepatic portosystemic shunt for refractory ascites","volume":"129","author":"D'Amico G","year":"2005","journal-title":"a meta-analysis"},{"key":"e_1_2_7_11_2","first-page":"298","article-title":"Transjugular intrahepatic portosystemic shunt patency and clinical outcome in patients with Budd\u2013Chiari syndrome","volume":"241","author":"Gandini R","year":"2006","journal-title":"covered versus uncovered stents"},{"key":"e_1_2_7_12_2","first-page":"1043","article-title":"Survival in patients undergoing transjugular intrahepatic portosystemic shunt","volume":"38","author":"Angermayr B","year":"2003","journal-title":"ePTFE-covered stentgrafts versus bare stents"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2007.01649.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03704.x"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.37073"},{"key":"e_1_2_7_16_2","first-page":"913","article-title":"Hepatic perfusion before and after the transjugular intrahepatic portosystemic shunt procedure","volume":"11","author":"Walser EM","year":"2000","journal-title":"impact on survival"},{"key":"e_1_2_7_17_2","first-page":"716","article-title":"Hepatic encephalopathy \u2013 definition, nomenclature, diagnosis, and quantification","volume":"35","author":"Ferenci P","year":"2002","journal-title":"final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21129"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20364"},{"key":"e_1_2_7_20_2","first-page":"685","article-title":"Transjugular intrahepatic portosystemic stent\u2010shunt (TIPSS)","volume":"9","author":"Kauffmann GW","year":"1999","journal-title":"technique and indications"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e318157e500"},{"key":"e_1_2_7_22_2","first-page":"437","article-title":"Portosystemic shunt via the left branch of portal vein for the prevention of encephalopathy following transjugular intrahepatic portosystemic shunt","volume":"10","author":"Chu J","year":"2002","journal-title":"Zhonghua Gan Zang Bing Za Zhi"},{"key":"e_1_2_7_23_2","first-page":"682","article-title":"PTFE\u2010encapsulated endovascular stent\u2010graft for transjugular intrahepatic portosystemic shunts","volume":"205","author":"Haskal ZJ","year":"1997","journal-title":"experimental evaluation"},{"key":"e_1_2_7_24_2","first-page":"539","article-title":"Stent\u2010grafts for revision of TIPS stenoses and occlusions","volume":"8","author":"Saxon RR","year":"1997","journal-title":"a clinical pilot study"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1478-3231.2009.02016.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1478-3231.2009.02016.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T18:38:52Z","timestamp":1697135932000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1478-3231.2009.02016.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,2]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1111\/j.1478-3231.2009.02016.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1478-3231.2009.02016.x","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,2]]}}}