{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T17:21:17Z","timestamp":1779211277894,"version":"3.51.4"},"reference-count":140,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T00:00:00Z","timestamp":1311897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cell death by apoptosis is a prominent feature in a variety of liver diseases. It is likely that apoptosis is the initial cellular response to hepatocyte and biliary injury, which then leads to the initiation of cellular and cytokine cascades culminating in hepatocyte death with subsequent fibrosis and cirrhosis. This sequence of events is of paramount clinical importance. Recently, soluble forms of the major histocompatibility complex class I\u2010related chains A and closely related B (<jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content> A and B) were reported to be increased in patients with a variety of liver diseases. <jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content> A and B are cell surface glycoproteins that function as indicators for cellular stress and thus activate circulating cytotoxic natural killer (<jats:styled-content style=\"fixed-case\">NK<\/jats:styled-content>) cells. The interaction between <jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content> A and B with their cognate receptor natural killer group 2 member D (<jats:styled-content style=\"fixed-case\">NKG<\/jats:styled-content>2D) culminates in enhanced liver cell death, which is mediated in part by apoptotic mechanisms. The present overview focuses on the role of the stress\u2010induced <jats:styled-content style=\"fixed-case\">NKG<\/jats:styled-content>2D ligands <jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content> A and B in diverse liver diseases. Critical insights into these complex relations may help to promote rationally based therapies in liver diseases. Importantly, we hope that this overview will help to stimulate further studies into mechanisms by which stress ligands mediate cell death and its sequale.<\/jats:p>","DOI":"10.1111\/j.1478-3231.2011.02608.x","type":"journal-article","created":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T10:00:22Z","timestamp":1311933622000},"page":"370-382","source":"Crossref","is-referenced-by-count":21,"title":["Role of stress\u2010induced <scp>NKG2D<\/scp> ligands in liver diseases"],"prefix":"10.1111","volume":"32","author":[{"given":"Alisan","family":"Kahraman","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology University Clinic Essen University of Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian D.","family":"Fingas","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University Clinic Essen University of Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wing\u2010Kin","family":"Syn","sequence":"additional","affiliation":[{"name":"Liver and Hepatobiliary Unit Queen Elizabeth Hospital Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Gerken","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University Clinic Essen University of Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Canbay","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University Clinic Essen University of Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri981"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2006.00435.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20204"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20433"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri854"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.15.1.535"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1189\/JLB.0309135"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2008.00859.x"},{"key":"e_1_2_12_10_1","first-page":"2041","article-title":"Soluble NKG2D ligands in hepatic autoimmune diseases and in benign diseases involved in marker metabolism","volume":"27","author":"Holdenrieder S","year":"2007","journal-title":"Anticancer Res"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2007.01.013"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00554.2007"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21419"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23320"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-5890(01)00107-9"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840210635"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0106-9543.2002.01595.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2006.11.010"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20051"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20479"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00497.2006"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-991510"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.182.5.1223"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.2174\/1566524033479555"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401437"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M003370200"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.038166"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23176"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(94)00608-3"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000153160.82975.86"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(97)00505-8"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.3.1678"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80222-8"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.161.7.3501"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.06.100"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22585"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22136"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.10.055"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22725"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.09.034"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-4079(19)32714-1"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(02)00230-9"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxh005"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1086\/586709"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(99)80297-9"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01389.x"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2008.00729.x"},{"key":"e_1_2_12_48_1","first-page":"1274","article-title":"Immunohistochemical detection of Fas and apoptosis in type\u20101 autoimmune hepatitis","volume":"50","author":"Seki S","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24194"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2010.01.011"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.11.046"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200507000-00013"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/0891693021000054093"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(01)00288-4"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.07.005"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.3109\/07357900903095714"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21964"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-1081-0"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2009.07.003"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214375"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23253"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.09.28"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.2004.0467"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.188.2.341"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.7.11.1689"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.4.1005"},{"key":"e_1_2_12_67_1","first-page":"373","article-title":"Hepatitis B virus down\u2010regulates expressions of MHC class I molecules on hepatoplastoma cell line","volume":"3","author":"Chen Y","year":"2006","journal-title":"Cell Mol Immunol"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1159\/000236009"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.07.033"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23515"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v113.pm9352872"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(97)80169-9"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510290445"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1086\/321005"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1086\/382189"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2005.00457.x"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22152"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20011124"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.01.006"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02334-06"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.05.047"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(02)00432-4"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14964-1"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1247128"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(04)01508-6"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpgasthep0038"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-44304"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9157-y"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.07.208"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02654-4"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-0789"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2009.02227.x"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.12.6879"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0602329"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2004.06.018"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2006.02.013"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.05.026"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1936"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1199"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.285.5428.727"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/35095564"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065X.2001.1810113.x"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.8.4098"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01112"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-01-0019"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21382"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-006-0167-1"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2006.02.008"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.12.6891"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-03-0918"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.2741\/1770"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2009.00541.x"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-4252"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065X.2001.1810114.x"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.10966"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2008-0185"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2009.10.038"},{"key":"e_1_2_12_118_1","first-page":"255","article-title":"14th International HLA and Immunogenetics Workshop Prospective Chronic Rejection Project: a three\u2010year follow\u2010up analysis","author":"Ozawa M","year":"2007","journal-title":"Clin Transpl"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21408"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21620"},{"key":"e_1_2_12_121_1","first-page":"1070","article-title":"Correlation between major histocompatibility complex class I\u2010related chain A gene alleles and graft rejective reaction in small intestine, liver and kidney transplantation","volume":"47","author":"He L","year":"2009","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2007.00625.x"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31816691ef"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.12.7335"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.164.4.7726038"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.164.4.7537016"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2005.03937.x"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.32.4.419"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.166.5.8615253"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.198.1.8539387"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21492"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197505000-00004"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200304000-00001"},{"key":"e_1_2_12_134_1","first-page":"119","article-title":"Obstructive jaundice due to biliary cast syndrome followed by orthotopic liver transplantation","volume":"48","author":"Bak SH","year":"2006","journal-title":"Korean J Gastroenterol"},{"key":"e_1_2_12_135_1","first-page":"212","article-title":"Biliary complications after liver transplantation: with special reference to the biliary cast syndrome and techniques of secondary duct repair","volume":"81","author":"Starzl TE","year":"1977","journal-title":"Surgery"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20331"},{"key":"e_1_2_12_137_1","first-page":"300","article-title":"Biliary cast syndrome: literature review and a single centre experience in liver transplant recipients","volume":"7","author":"Srinivasaiah N","year":"2008","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22007"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2009.06.003"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-05-223172"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31818b2316"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1478-3231.2011.02608.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1478-3231.2011.02608.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T07:40:35Z","timestamp":1700552435000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1478-3231.2011.02608.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,29]]},"references-count":140,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1111\/j.1478-3231.2011.02608.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1478-3231.2011.02608.x","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,29]]}}}