{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:08:06Z","timestamp":1791806886447,"version":"4.3.4"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T00:00:00Z","timestamp":1152230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives:\u2002<\/jats:bold> To assess the demographics, efficacy and safety of lipiodol flushing fertility treatment.<\/jats:p><jats:p><jats:bold>Design:\u2002<\/jats:bold> Prospective observational study.<\/jats:p><jats:p><jats:bold>Setting:\u2002<\/jats:bold> Secondary level care infertility clinic and radiology centre based in Auckland, New Zealand.<\/jats:p><jats:p><jats:bold>Population:\u2002<\/jats:bold> The first cohort of 100 New Zealand women with infertility to undergo lipiodol flushing as an innovative fertility treatment.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Women received lipiodol flushing performed by a hysterosalpingogram technique and were followed up at 6 months.<\/jats:p><jats:p><jats:bold>Main outcome measures:\u2002<\/jats:bold> Clinical pregnancy at 6 months post\u2010treatment; and live birth or ongoing pregnancy.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The overall pregnancy rate was 30% and the live birth or ongoing pregnancy rate 27%. For women under 40 years old, a 32% pregnancy rate and a 25% live birth or ongoing pregnancy rate were seen in women with unexplained infertility, and a 50% pregnancy rate and a 47% live birth or ongoing pregnancy rate were seen in women with endometriosis. Of women aged 40 years and older, the pregnancy rate was 13% and the live birth or ongoing pregnancy rate was 13%. The pregnancy rates included those occurring after additional interventions, such as intrauterine insemination and <jats:italic>in vitro<\/jats:italic> fertilisation, accounting for 12 of the 30 pregnancies. There were no treatment complications.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> This study provides further evidence of the efficacy and safety of lipiodol flushing fertility treatment.<\/jats:p>","DOI":"10.1111\/j.1479-828x.2006.00595.x","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T23:30:57Z","timestamp":1152315057000},"page":"293-297","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["After the FLUSH trial: A prospective observational study of lipiodol flushing as an innovative treatment for unexplained and endometriosis\u2010related infertility"],"prefix":"10.1111","volume":"46","author":[{"given":"Kira","family":"BRENT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy E.","family":"HADDEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"WESTON\u2010WEBB","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil P.","family":"JOHNSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,7]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)30725-7"},{"key":"e_1_2_7_3_2","article-title":"Tubal flushing for subfertility","author":"Johnson N","year":"2006","journal-title":"The Cochrane Database of Syst Rev"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)56578-9"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh418"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.179.1.1848715"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.2165\/00024677-200504040-00004"},{"key":"e_1_2_7_8_2","unstructured":"BryantJ SullivanEA DeanJH.Assisted Reproductive Technology in Australia and New Zealand 2002. 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