{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T05:46:38Z","timestamp":1697175998450},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T00:00:00Z","timestamp":1152230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective:\u2002<\/jats:bold> To evaluate clinicians\u2019 beliefs concerning the effectiveness of lipiodol flushing as a treatment for unexplained infertility, and to integrate these prior beliefs with evidence from randomised trials.<\/jats:p><jats:p><jats:bold>Design:\u2002<\/jats:bold> Survey.<\/jats:p><jats:p><jats:bold>Setting:\u2002<\/jats:bold> Specialists in Australasian <jats:italic>in vitro<\/jats:italic> fertilisation (IVF) clinics in 2001.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> One of two types of structured survey was used to gather information from fertility specialists in Australasian IVF clinics. Prior beliefs were captured graphically and textually from responses.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Nineteen specialists returned questionnaires. Eighteen of the 19 specialists believed that lipiodol flushing was more likely to be beneficial than harmful. The most widely held prior belief, reflected in both textual and numerical responses, was that lipiodol was likely to produce a small beneficial response. The credible limits of this belief were compatible with a reasonable fertility benefit, as more than 50% believed that a 1.5\u2010fold increase in pregnancy rate was plausible. The two surveys found that a 1.2\u2010fold or 1.4\u2010fold increase in pregnancy rate was the median expected level of benefit at which clinicians would have been inclined to recommend lipiodol flushing to their patients (combined range 1.1\u2010 to 2.3\u2010fold) \u2013 new evidence suggests that for women with endometriosis but otherwise unexplained infertility, these levels of benefit are exceeded.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Among Australasian fertility specialists there is variation in prior beliefs concerning the effectiveness of lipiodol flushing as a treatment for unexplained infertility and in the expected level of benefit at which clinicians are inclined to recommend this treatment. Generalisability of these beliefs remains uncertain owing to a low study response rate.<\/jats:p>","DOI":"10.1111\/j.1479-828x.2006.00596.x","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T23:30:57Z","timestamp":1152315057000},"page":"298-304","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Survey of Australasian clinicians\u2019 prior beliefs concerning lipiodol flushing as a treatment for infertility: A Bayesian study"],"prefix":"10.1111","volume":"46","author":[{"given":"Neil P.","family":"JOHNSON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalie A.","family":"FISHER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"BRAUNHOLTZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne R.","family":"GILLETT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"LILFORD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.54.10.731"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16809-8"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)30725-7"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)56578-9"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003718.pub2"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.1.r00ja2353"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh418"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.11.065"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0004-8666.2002.00271.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.2165\/00024677-200504040-00004"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","unstructured":"BrentK HaddenWE Weston\u2010WebbM JohnsonNP.After the FLUSH trial: a prospective observational study of lipiodol flushing as an innovative treatment for unexplained and endometriosis\u2010related infertility.Aust NZ J Obstet Gynaecol2006;46:293\u2013297.","DOI":"10.1111\/j.1479-828X.2006.00595.x"},{"key":"e_1_2_6_13_2","first-page":"406","article-title":"The FLUSH trial \u2013 a randomised trial of lipiodol flushing for unexplained subfertility by hysterosalpingography","volume":"43","author":"Johnson N","year":"2003","journal-title":"Aust NZ J Obstet Gynaecol"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1479-828X.2006.00596.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1479-828X.2006.00596.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T07:01:20Z","timestamp":1697094080000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1479-828X.2006.00596.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,7]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["10.1111\/j.1479-828X.2006.00596.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1479-828x.2006.00596.x","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,7]]},"assertion":[{"value":"2006-07-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}