{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T14:45:05Z","timestamp":1770561905540,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,4,9]],"date-time":"2012-04-09T00:00:00Z","timestamp":1333929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Adnexal masses detected in breast cancer survivors are of particular concern because of the increased risk of ovarian malignancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This study was performed to analyse adnexal masses among women with breast cancer with regard to variables predictive of malignancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included women with breast cancer who had undergone surgery for an adnexal mass between 2002 and 2010 at <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>acettepe <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital. A total of 45 consecutive women with a mean age of 47.3\u00a0years (range 25\u201376) were analysed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 45 cases reviewed, benign ovarian pathology was found in 35 cases (77.8%) and malignant ovarian neoplasms were found in 10 cases (22.2%). A simple ovarian cyst was observed in 25 cases (71.4%) as the most common type of benign pathology. Of the 10 cases with malignancy, 5 (50%) had primary ovarian carcinoma, while the remaining five women had breast carcinoma metastases to the ovary. Complex mass at ultrasonography, increased <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content> 125 level and oestrogen receptor\u2013negative tumour were found to be the significant predictors of ovarian malignancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although an adnexal mass in a woman with breast cancer is most commonly a benign ovarian cyst, the overall risk of ovarian malignancy is increased with breast cancer. An adnexal mass with complex architecture detected by ultrasonography and high <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content> 125 level were the strongest risk factors associated with increased risk of malignancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1479-828x.2012.01430.x","type":"journal-article","created":{"date-parts":[[2012,4,9]],"date-time":"2012-04-09T05:22:24Z","timestamp":1333948944000},"page":"266-269","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Adnexal masses in women with breast cancer"],"prefix":"10.1111","volume":"52","author":[{"given":"Zafer Selcuk","family":"Tuncer","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokhan","family":"Boyraz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilker","family":"Selcuk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volkan","family":"Kaynaro\u011flu","sequence":"additional","affiliation":[{"name":"Department of General Surgery Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz","family":"\u00d6z\u0131\u015f\u0131k","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.56.2.106"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000154162.51442.14"},{"key":"e_1_2_5_4_1","first-page":"609","article-title":"Ovarian cancer: an overview","volume":"80","author":"Roett MA","year":"2009","journal-title":"Am Fam Physician"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.1.r00jl15242"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24807"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1993.01420240052009"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1997.4720"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000313921"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2008.19.4.256"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02630-3"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.10.026"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1479-828X.2012.01430.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1479-828X.2012.01430.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T07:08:02Z","timestamp":1700550482000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1479-828X.2012.01430.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,9]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1479-828X.2012.01430.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1479-828x.2012.01430.x","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,9]]},"assertion":[{"value":"2011-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-02-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-04-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}