{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T00:23:31Z","timestamp":1793579011652,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,5,4]],"date-time":"2012-05-04T00:00:00Z","timestamp":1336089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Child bearing in the later reproductive years has become increasingly common in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia with potential implications for clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To examine pregnancy outcomes for nulliparous women of advanced maternal age with singleton pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective population\u2010based cohort study was conducted to compare the pregnancy outcomes for women aged 35\u201339\u00a0years and \u226540\u00a0years with women aged 25\u201329\u00a0years, analysing 34\u00a0695 records from the <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outh <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralian <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>erinatal <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>atabase between 1998 and 2008.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pre\u2010existing hypertension [relative risks (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>) 1.98 and 2.94 for women aged 35\u201339\u00a0years and \u226540\u00a0years, respectively], placenta praevia (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 2.88 and 3.68), suspected intrauterine growth restriction (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.33 and 1.77) and gestational diabetes (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.97 and 2.53) increased with age. Women of advanced maternal age were more likely to have not laboured prior to birth (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 2.19 and 3.28), be induced (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.12 and 1.27) and have a breech presentation (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.57 and 1.60). The likelihood of fetal distress increased with advancing maternal age (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.15 and 1.24). Regression analyses revealed women of advanced maternal age were significantly more likely to have small for gestational age infants [adjusted odds ratios (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content>) 1.26 and 1.50], preterm birth (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 1.26 and 1.43), elective caesarean [relative risk ratios (<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content>) 2.55 and 4.52], emergency caesarean (<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content> 1.59 and 2.21) and experience a perinatal death (<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content> 1.94 and 2.18).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The likelihood of pre\u2010existing medical conditions, obstetric complications, adverse labour and birth outcomes and complications increased with advancing maternal age. 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