{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T02:10:00Z","timestamp":1771985400975,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T00:00:00Z","timestamp":1348444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Multiple factors appear to affect bone mineral density (<jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>) during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to determine the relationships between <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> of the os calcaneus as measured by quantitative ultrasound (<jats:styled-content style=\"fixed-case\">QUS<\/jats:styled-content>) and levels of vitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>3, parathyroid hormone (<jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content>), albumin (<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>lb), calcium (<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>a), phosphorus (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>) and alkaline phosphatase (<jats:styled-content style=\"fixed-case\">ALP<\/jats:styled-content>) in a group of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Multiple parameters, including density of the os calcaneus, were recorded for a group of 130 women in early (mean gestation, 16.09\u00a0\u00b1\u00a02.65\u00a0weeks) and late (mean gestation, 32.01\u00a0\u00b1\u00a03.45\u00a0weeks) stages of pregnancy; 139 nonpregnant women served as controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bone mineral density was lower in pregnant women than in controls at both early and late stages of pregnancy. Levels of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>a, <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ALP<\/jats:styled-content> were significantly negatively correlated with <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> over the course of pregnancy. Levels of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>3, <jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content> and Alb showed a falling trend from early to late pregnancy as with <jats:styled-content style=\"fixed-case\">QUS BMD<\/jats:styled-content> of the os calcaneus, but the correlations were not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Many factors are correlated with <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>. We suggest that levels of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>a and <jats:styled-content style=\"fixed-case\">ALP<\/jats:styled-content> should be included in the routine examination of pregnant women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1479-828x.2012.01477.x","type":"journal-article","created":{"date-parts":[[2012,9,25]],"date-time":"2012-09-25T01:51:38Z","timestamp":1348537898000},"page":"571-575","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Vitamin <scp>D<\/scp> levels and other factors related to bone mineral density during pregnancy"],"prefix":"10.1111","volume":"52","author":[{"given":"Hongfang","family":"Shao","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Sixth People's Hospital Shanghai Jiaotong University Shanghai 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