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This article summarises the consensus developed by a group of Australasian subspecialists in reproductive endocrinology and infertility (the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralasian <jats:styled-content style=\"fixed-case\">CREI<\/jats:styled-content> Consensus Expert Panel on Trial evidence group) on the evidence concerning the management of endometriosis in infertility. Endometriosis impairs fertility by causing a local inflammatory state, inducing progesterone resistance, impairing oocyte release and reducing sperm and embryo transport. Medical treatments have a limited role, whereas surgical and assisted reproductive treatments improve pregnancy rates. The role of surgery for deep infiltrative endometriosis and repeat surgery requires further evaluation and there is insufficient evidence for the use of anti\u2010adhesives to improve fertility. Intrauterine insemination (<jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content>) and <jats:italic>in vitro<\/jats:italic> fertilisation (<jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>) improve pregnancy rates but women with endometriosis have lower pregnancy rates than those with other causes of infertility. The decision about whether to operate or pursue assisted reproduction will depend on a variety of factors such as the patient's symptoms, the presence of complex masses on ultrasound, ovarian reserve and ovarian access for <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>, risk of surgery and cost. Some women with infertility and endometriosis may benefit from a combination of assisted reproduction and surgery.<\/jats:p>","DOI":"10.1111\/j.1479-828x.2012.01480.x","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T09:49:28Z","timestamp":1348998568000},"page":"513-522","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Endometriosis and Infertility \u2013 a consensus statement from <scp>ACCEPT<\/scp> (Australasian <scp>CREI<\/scp> Consensus Expert Panel on Trial evidence)"],"prefix":"10.1111","volume":"52","author":[{"given":"Juliette","family":"Koch","sequence":"first","affiliation":[{"name":"IVF Australia Bondi Junction New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Rowan","sequence":"additional","affiliation":[{"name":"Genea Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luk","family":"Rombauts","sequence":"additional","affiliation":[{"name":"Department of O&amp;G Monash University Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusch","family":"Yazdani","sequence":"additional","affiliation":[{"name":"QFG Research Foundation University of Queensland St Lucia Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chapman","sequence":"additional","affiliation":[{"name":"Department of O&amp;G University of New South Wales Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Johnson","sequence":"additional","affiliation":[{"name":"University of Auckland Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-41330"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.01.019"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00081-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)49474-4"},{"key":"e_1_2_6_6_1","first-page":"253","article-title":"The effect of laproscopic ablation or danocrine on pregnancy rates in patients with stage I or II endometriosis undergoing donor insemination","volume":"80","author":"Toma S","year":"1992","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh418"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.81.8.3112"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.6.2553"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.6.1250"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)81915-2"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00507-5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(82)90217-4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022568331845"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.7.1825"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022526002421"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022574221115"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013111200251"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-1692"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-0043"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-007-9116-y"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)48674-7"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)03112-6"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2011.01300.x"},{"key":"e_1_2_6_25_1","first-page":"CD000155","article-title":"Ovulation suppression for endometriosis for women with subfertility","author":"Hughes E","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem275"},{"key":"e_1_2_6_27_1","first-page":"CD007677","article-title":"Pentoxifylline versus medical therapies for subfertile women with endometriosis","author":"Lv D","year":"2009","journal-title":"Cochrane Database Sys Rev"},{"key":"e_1_2_6_28_1","unstructured":"Royal College of Obstetricians and Gynaecologists.Green\u2010top Guideline No. 24: Endometriosis Investigation and Mangaement. 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