{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T07:12:34Z","timestamp":1698736354315},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>In September 2009, <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia implemented mandatory folic acid fortification of wheat flour for bread\u2010making to reduce the incidence of neural tube defects. Our study aimed to establish baseline folate status data in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal and non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>estern <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who presented at a health service or collection centre for blood tests were invited to participate. One hundred and ninety\u2010one <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginals and 159 non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginals were recruited between <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril 2008 and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2009. Participants completed a five\u2010minute questionnaire and had blood taken for red blood cell (<jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>) folate and serum vitamin <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>12. Data were analysed using <jats:styled-content style=\"fixed-case\">SPSS<\/jats:styled-content> (version 17.0.2, SPSS Inc., Chicago, IL, USA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten per cent (95% confidence intervals (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>): 5, 19) of the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal women participants and 26% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 16, 40) of men had <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> folate concentrations below 250\u00a0ng\/mL, the cut\u2010off associated with folate deficiency. None of the non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal women (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0, 4) and 4% of the non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal men (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2, 12) had <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> folate concentrations below 250\u00a0ng\/mL. All participants were vitamin <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>12 replete. None of the 96 <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal and 8% of non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal women aged 16\u201344 reported consumption of supplements with a daily intake of &gt;400\u00a0\u03bcg folic acid during the previous week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and implications<\/jats:title><jats:p>This study established a baseline of <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> folate, folate consumption and supplement use in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal and non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal groups. We identified 10% of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal women and none of non\u2010<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal women participants with low folate concentrations. The higher prevalence of folate deficiency in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>boriginal participants suggests they are more likely to benefit from a universal program of folate fortification.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1479-828x.2012.01484.x","type":"journal-article","created":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T06:01:13Z","timestamp":1349848873000},"page":"26-31","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Baseline investigations of folate status in <scp>A<\/scp>boriginal and non\u2010<scp>A<\/scp>boriginal <scp>W<\/scp>est <scp>A<\/scp>ustralians prior to the introduction of mandatory fortification"],"prefix":"10.1111","volume":"53","author":[{"given":"Susannah J.","family":"Maxwell","sequence":"first","affiliation":[{"name":"Department of Health Office of Population Health Genomics Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate J.","family":"Brameld","sequence":"additional","affiliation":[{"name":"Department of Health Peel and Rockingham Kwinana Mental Health Service Perth Western Australia Australia"},{"name":"Centre for Population Health Research Curtin Health Innovation Research Institute Curtin University of Technology Bentley Western Australia Australia"},{"name":"School of Population Health University of Western Australia Crawley Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Bower","sequence":"additional","affiliation":[{"name":"Western Australian WA Register of Developmental Anomalies King Edward Memorial Hospital for Women Subiaco Western Australia Australia"},{"name":"Telethon Institute for Child Health Centre for Child Health Research The University of Western Australia Crawley Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"D'Antoine","sequence":"additional","affiliation":[{"name":"Menzies School of Health Charles Darwin University Darwin Northern Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siobhan","family":"Hickling","sequence":"additional","affiliation":[{"name":"School of Population Health University of Western Australia Crawley Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Marley","sequence":"additional","affiliation":[{"name":"The Rural Clinical School of Western Australia The University of Western Australia Crawley Western Australia Australia"},{"name":"Kimberley Aboriginal Medical Services Council Inc Broome Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Department of Health Office of Population Health Genomics Perth Western Australia Australia"},{"name":"Centre for Population Health Research Curtin Health Innovation Research Institute Curtin University of Technology Bentley Western Australia Australia"},{"name":"School of Pathology &amp; Laboratory Medicine University of Western Australia Crawley Western Australia Australia"},{"name":"School of Women's &amp; Infants' Health University of Western Australia Crawley Western Australia 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