{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T19:28:48Z","timestamp":1792870128967,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T00:00:00Z","timestamp":1348099200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychogeriatrics"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> Patients with major stroke are often left with disability and may have depression and dementia during the recovery phase. Rehabilitation programmes have been shown to improve short\u2010term physical outcome, but their long\u2010term effectiveness and impact on dementia and depression are uncertain.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> We performed a 6\u2010month randomized controlled trial of a home rehabilitation programme and compared it with the standard care patients with recent ischemic stroke receive. The intervention group received home\u2010based physical therapy once a month for 6\u2003months, along with educational support, counselling and audiovisual materials. The control group received rehabilitation as prescribed by a physician and educational materials upon discharge from hospital. The primary measurement was a change in Barthel Index. Secondary measurements were the Hospital Anxiety and Depression Scale (HADS) and Thai Mini\u2010Mental State Examination.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Of the 68 screened patients, 60 patients were enrolled. At baseline, there was no significant difference in patient characteristics between the two groups. Over 2\u2003years, the mean Barthel Index and Hospital Anxiety and Depression Scale were significantly improved in the intervention group compared to the control group (Barthel Index mean: from 31.7 \u00b1 5.9 to 97.2 \u00b1 2.8 vs from 33.2 \u00b1 4.8 to 76.4 \u00b1 9.4, <jats:italic>P<\/jats:italic> &lt; 0.001; Hospital Anxiety and Depression Scale mean: from 16.1 \u00b1 7.6 to 9.1 \u00b1 0.3 vs 16.4 \u00b1 4.9 to 9.1 \u00b1 0.3, <jats:italic>P<\/jats:italic>= 0.003). Depression was strongly associated with being dependent on others. However, the Thai Mini\u2010Mental State Examination in both groups did not significantly differ (Thai Mini\u2010Mental State Examination mean: from 24.4 \u00b1 2.0 to 24.6 vs 23.8 \u00b1 1.9 to 24.1 \u00b1 0.3, <jats:italic>P<\/jats:italic>= 0.068). There was no significant interaction between baseline characteristics and treatment outcome.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> At 2\u2003years follow\u2010up, it was evident that a 6\u2010month home rehabilitation programme after ischemic stroke improved functional outcome and reduced incidence of depression, but not dementia.<\/jats:p>","DOI":"10.1111\/j.1479-8301.2012.00412.x","type":"journal-article","created":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T10:41:58Z","timestamp":1348137718000},"page":"193-199","source":"Crossref","is-referenced-by-count":36,"title":["Randomized controlled trial of home rehabilitation for patients with ischemic stroke: impact upon disability and elderly depression"],"prefix":"10.1111","volume":"12","author":[{"given":"Pakaratee","family":"CHAIYAWAT","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kongkiat","family":"KULKANTRAKORN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2005.12.012"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2007.11.005"},{"key":"e_1_2_6_4_2","first-page":"497","article-title":"Epidemiology of stroke in the elderly in Thailand","volume":"81","author":"Viriyavejakul A","year":"1998","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_6_5_2","first-page":"51","article-title":"Prediction of outcomes following rehabilitation of stroke patients","volume":"2","author":"Johnston 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application of upper\u2010extremity constraint\u2010induced movement therapy in a patient with subacute stroke","volume":"79","author":"Blanton S","year":"1999","journal-title":"Phys 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