{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:00:39Z","timestamp":1787014839609,"version":"build-2736575974"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,9,5]],"date-time":"2006-09-05T00:00:00Z","timestamp":1157414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background:\u2002<\/jats:bold>\n                    Recurrence infection following successful eradication of\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    is usually low, except for countries with high prevalence of\n                    <jats:italic>H.\u00a0pylori.<\/jats:italic>\n                    The aim of this study was to verify\n                    <jats:italic>H.\u00a0pylori<\/jats:italic>\n                    recurrence rate in patients with duodenal ulcer after eradication and the possible relationship with environmental factors, histologic pattern of the mucosa and bacterial genotype.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Materials and methods:\u2002<\/jats:bold>\n                    One\u2010hundred and ninety\u2010four patients with an active duodenal ulcer and who were successfully treated for\n                    <jats:italic>H.\u00a0pylori<\/jats:italic>\n                    infection from 1990 to 1999 were studied. A questionnaire was answered about their living conditions, and a\n                    <jats:sup>14<\/jats:sup>\n                    C\u2010urea breath test was performed. Patients with a positive breath test underwent an upper endoscopy to investigate for possible ulcer recurrence; gastric biopsy samples were than collected for rapid urease test and for histologic assessment.\n                    <jats:italic>H.\u00a0pylori vac<\/jats:italic>\n                    A and\n                    <jats:italic>cag<\/jats:italic>\n                    A genotype was determined by polymerase chain reaction in those samples with positive urease test.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    <jats:italic>H.\u00a0pylori<\/jats:italic>\n                    infection was detected in 11 patients (recurrence rate of 5.7%) that were not associated with the type of bacterial virulence. In 10 patients the ulcer was healed and all of them were clinically asymptomatic. In eight, histology showed an intensification of gastritis. All 11 patients had adequate housing and sanitary conditions and no other risk for\n                    <jats:italic>H.\u00a0pylori<\/jats:italic>\n                    recurrence was identified.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:\u2002<\/jats:bold>\n                    The recurrence rate of\n                    <jats:italic>H.\u00a0pylori<\/jats:italic>\n                    in Brazil was higher than that reported in developed countries, but lower than usually reported in developing ones. Ulcer relapse rarely occurs even in long\u2010term follow up.\n                  <\/jats:p>","DOI":"10.1111\/j.1523-5378.2006.00434.x","type":"journal-article","created":{"date-parts":[[2006,9,5]],"date-time":"2006-09-05T14:29:23Z","timestamp":1157466563000},"page":"431-435","source":"Crossref","is-referenced-by-count":8,"title":["<i>Helicobacter pylori<\/i>\n                    Recurrence in Patients with Duodenal Ulcer: Clinical, Endoscopic, Histologic, and Genotypic Aspects. A 10\u2010Year Brazilian Series"],"prefix":"10.1111","volume":"11","author":[{"given":"Jaime N.","family":"Eisig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schlioma","family":"Zaterka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando M.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rejane","family":"Mattar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom\u00e1s N.","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e1udio L.","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kioshi","family":"Iriya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio A.","family":"Laudanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim P.P.","family":"Moraes\u2010Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,9,5]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(88)90606-3"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529609094744"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1990.tb136833.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v113.pm9322501"},{"key":"e_1_2_5_6_2","first-page":"529","article-title":"Helicobacter pylori reinfection rate, in patients with cured duodenal ulcer","volume":"89","author":"Borody TJ","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529209000173"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529609094544"},{"key":"e_1_2_5_9_2","first-page":"144","article-title":"Helicobacter pylori in the developing world","volume":"12","author":"Sack RB","year":"1994","journal-title":"J Diarrhoeal Dis Res"},{"key":"e_1_2_5_10_2","first-page":"77","article-title":"Helicobacter pylori infection in developing countries","volume":"57","author":"Guisset M","year":"1997","journal-title":"Med Trop"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018827322470"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529209000088"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2001000600008"},{"key":"e_1_2_5_14_2","first-page":"138","article-title":"Recorr\u00eancia da infec\u00e7\u00e3o por H. pylori em portadores de \u00falcera p\u00e9ptica submetidos \u00e0 erradica\u00e7\u00e3o da bact\u00e9ria","volume":"18","author":"Chehter L","year":"1999","journal-title":"GED"},{"key":"e_1_2_5_15_2","first-page":"1596","article-title":"Reinfection by H. pylori in a developing country. 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