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The possible mechanism might be due to <jats:italic>H. pylori<\/jats:italic> antigens causing intermittent vasospasm of arterioles, which also played roles in the development of liver cirrhosis. Migraine, a functional vascular disease, was observed in many patients with cirrhosis in the clinic. This study aimed to assess the effects of <jats:italic>H. pylori<\/jats:italic> eradication on migraine symptoms in patients with hepatitis\u2010B\u2010virus\u2010related cirrhosis. The results clearly showed that the intensity, duration, and frequency of attacks of migraine were significantly reduced in all the patients in whom <jats:italic>H. pylori<\/jats:italic> has been eradicated. 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