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In 2008, interesting articles on the association of <jats:italic>H. pylori<\/jats:italic> infection with these disorders were presented, some of which intended to reveal the mechanisms of inter\u2010individual differences in response to <jats:italic>H. pylori<\/jats:italic> infection, and have demonstrated that genetic differences in host and bacterial factors as well as environmental factors account for these differences. A decline in the occurrence of peptic ulcer related to <jats:italic>H. pylori<\/jats:italic> was confirmed. An inverse relationship between <jats:italic>H. pylori<\/jats:italic> infection and GERD was also confirmed but the impact of gastric atrophy on the prevention of GERD remained debatable. For NSAID\u2010induced gastric injury, eradication of <jats:italic>H. pylori<\/jats:italic> infection has been recommended. During this year, eradication of <jats:italic>H. pylori<\/jats:italic> infection was recommended for patients treated with antiplatelet therapy as well as aspirin and NSAID. It was also reported that for patients with functional dyspepsia, eradication of <jats:italic>H. pylori<\/jats:italic> offers a modest but significant benefit.<\/jats:p>","DOI":"10.1111\/j.1523-5378.2009.00697.x","type":"journal-article","created":{"date-parts":[[2009,8,25]],"date-time":"2009-08-25T09:54:27Z","timestamp":1251194067000},"page":"29-35","source":"Crossref","is-referenced-by-count":13,"title":["<i>Helicobacter pylori<\/i> and Non\u2010malignant 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