{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:49:51Z","timestamp":1761630591098},"reference-count":45,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2011,9,7]],"date-time":"2011-09-07T00:00:00Z","timestamp":1315353600000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Helicobacter"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Research published over the past year has documented the continued decline of <jats:italic>Helicobacter pylori<\/jats:italic>\u2010related peptic ulcer disease and increased recognition of non\u2010<jats:italic>H.\u00a0pylori<\/jats:italic>, non\u2010steroidal anti\u2010inflammatory drugs ulcer disease \u2013 idiopathic ulcers. Despite reduced prevalence of uncomplicated PUD, rates of ulcer complications and associated mortality remain stubbornly high. The role of <jats:italic>H.\u00a0pylori<\/jats:italic> in functional dyspepsia is unclear, with some authors considering <jats:italic>H.\u00a0pylori<\/jats:italic>\u2010associated nonulcer dyspepsia a distinct organic entity. There is increasing acceptance of an inverse relationship between <jats:italic>H.\u00a0pylori<\/jats:italic> and gastroesophageal reflux disease (GERD), but little understanding of how GERD might be more common\/severe in <jats:italic>H.\u00a0pylori<\/jats:italic>\u2010negative subjects. Research has focused on factors such as different <jats:italic>H.\u00a0pylori<\/jats:italic> phenotypes, weight gain after <jats:italic>H.\u00a0pylori<\/jats:italic> eradication, and effects on hormones such as ghrelin that control appetite.<\/jats:p>","DOI":"10.1111\/j.1523-5378.2011.00878.x","type":"journal-article","created":{"date-parts":[[2011,9,7]],"date-time":"2011-09-07T09:30:03Z","timestamp":1315387803000},"page":"33-37","source":"Crossref","is-referenced-by-count":27,"title":["<i>Helicobacter pylori<\/i> and Nonmalignant Diseases"],"prefix":"10.1111","volume":"16","author":[{"given":"Alaa","family":"Alakkari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Zullo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humphrey J.","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,7]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06534.x"},{"issue":"1","key":"e_1_2_7_3_2","first-page":"S116","article-title":"Helicobacter pylori","volume":"89","author":"Marshall BJ","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-200724100-00003"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199701000-00002"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.167_b.x"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-0028-6"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1083-4389.2004.00219.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.meg.0000108367.19243.73"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.04131.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.11.013"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-011-0085-9"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2010.03.019"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.101634"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.03960.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04563.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1159\/000323958"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.4321\/S1130-01082011000100004"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.70608"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.2"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-152-2-201001190-00009"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7429"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e328346a559"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.059"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06647.x"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.77244"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365521003632576"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06649.x"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06629.x"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e328317b89e"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.05982.x"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06635.x"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.106666"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(11)60593-8"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2007.01.009"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i9.1234"},{"key":"e_1_2_7_37_2","first-page":"69","article-title":"Helicobacter pylori and gastroesophageal reflux disease: a cross sectional study","volume":"58","author":"Scarpa M","year":"2011","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_38_2","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3390\/medicina46070065","article-title":"De novo esophagitis in duodenal ulcer patients related to pre\u2010existing reflux symptoms, smoking, and patient age, but not related to Helicobacter pylori eradication: a one year follow up study","volume":"46","author":"Jonaitis L","year":"2010","journal-title":"Medicina (Kaunas)"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-010-0078-0"},{"key":"e_1_2_7_40_2","first-page":"461","article-title":"Local acid production and Helicobacter pylori: a unifying hypothesis of gastroduodenal disease","volume":"7","author":"Lee A","year":"1995","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2010.16.3.243"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e318167b88a"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.147090"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0359-5"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04610.x"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i10.1249"}],"container-title":["Helicobacter"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1523-5378.2011.00878.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1523-5378.2011.00878.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T10:58:42Z","timestamp":1694602722000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1523-5378.2011.00878.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":45,"journal-issue":{"issue":"s1","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1111\/j.1523-5378.2011.00878.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1523-5378.2011.00878.x","archive":["Portico"],"relation":{},"ISSN":["1083-4389","1523-5378"],"issn-type":[{"value":"1083-4389","type":"print"},{"value":"1523-5378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}