{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T13:49:03Z","timestamp":1770990543901,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,8,19]],"date-time":"2011-08-19T00:00:00Z","timestamp":1313712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Childhood vaccines are a routine part of pediatric care in the United States; clinicians must be able to recognize and interpret associated localized adverse reactions. Redness and induration at the site of injection are commonly reported and are considered to be the result of local inflammation or hematoma formation, although other atypical reactions can occur. We report the case of a 6\u2010month\u2010old infant who developed subcutaneous nodules at the sites of his 4\u2010 and 6\u2010month Pentacel (DTaP\/Hib\/IPV, diphtheria, tetanus, acellular pertussis, <jats:italic>Haemophilus<\/jats:italic> b conjugate, and inactivated poliovirus vaccine) and 6\u2010month Prevnar (heptavalent pneumococcal vaccine) injections. Infectious disease and immunodeficiency examinations were unremarkable. Aluminum contact allergy was considered, and contact allergy testing confirmed sensitivity to aluminum. Although rare, aluminum contact allergy after routine immunization can occur and should be considered in the differential diagnosis of persistent subcutaneous nodules after vaccination.<\/jats:p>","DOI":"10.1111\/j.1525-1470.2011.01541.x","type":"journal-article","created":{"date-parts":[[2011,8,20]],"date-time":"2011-08-20T05:23:51Z","timestamp":1313817831000},"page":"68-72","source":"Crossref","is-referenced-by-count":15,"title":["Local Vaccine Site Reactions and Contact Allergy to Aluminum"],"prefix":"10.1111","volume":"29","author":[{"given":"Mara G.","family":"Beveridge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid C.","family":"Polcari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Burns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amos","family":"Adler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Hendrickson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah L.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,8,19]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.08.039"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2004.03.013"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.01983.x"},{"key":"e_1_2_4_5_2","first-page":"182","article-title":"Subcutaneous nodule after vaccination with an aluminum\u2010containing vaccine","volume":"17","author":"Avcin S","year":"2008","journal-title":"Acta Dermatovenerol Alp Panonica Adriat"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e318185a691"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01474.x"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01394.x"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.0654c.x"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.131.12.1421"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2005.tb06922.x"},{"key":"e_1_2_4_12_2","volume-title":"Epidemiology and prevention of vaccine\u2010preventable diseases","author":"Centers for Disease Control and Prevention","year":"2009"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2007.04.012"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199305000-00003"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI3312"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01206501-200509000-00004"},{"key":"e_1_2_4_17_2","article-title":"Systemic contact dermatitis in children: how an avoidance diet can make a difference","author":"Matiz C","year":"2010","journal-title":"Pediatr Dermatol"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2007.00409.x"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01200.x"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.4161\/hv.4.5.6438"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2009.10.005"},{"key":"e_1_2_4_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01663.x"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1525-1470.2011.01541.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1525-1470.2011.01541.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T13:49:20Z","timestamp":1697291360000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1525-1470.2011.01541.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,19]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1111\/j.1525-1470.2011.01541.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1525-1470.2011.01541.x","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,19]]}}}