{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T05:07:31Z","timestamp":1697432851195},"reference-count":8,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,1,20]],"date-time":"2006-01-20T00:00:00Z","timestamp":1137715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold><jats:bold> Background:<\/jats:bold> In experimental reports, blood flow redistribution occurred during cardiopulmonary bypass (CPB) and perfusion pressure was restored by vasoconstrictor administration without improving splanchnic perfusion. The influence of vasoconstrictor administration during CPB was clinically examined.<\/jats:p><jats:p><jats:bold>Materials and Methods:<\/jats:bold> Twenty\u2010two consecutive pediatric CPB cases of ventricular septal defect without blood transfusion were divided into two groups, depending upon whether a vasoconstrictor was administered during CPB or not (<jats:italic>n<\/jats:italic>\u2003=\u20037 vs. 15). Bypass flow and systemic perfusion pressure during CPB were maintained at 2.5\u2003L\/m<jats:sup>2<\/jats:sup>\/min and not lower than 30\u2003mm\u2003Hg by vasoconstrictor administration, respectively.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Although preoperative state and CPB conditions were comparable between the two groups, more sodium bicarbonate was administered (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.05); duration from the operation to extubation was longer (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.05); and bowel movement occurred later in the vasoconstrictor\u2010administered group than in the control group. <jats:bold>Conclusions:<\/jats:bold> Vasoconstrictor administration during CPB may deteriorate the acid\u2013base balance and the postoperative state in infants and children.<\/jats:p>","DOI":"10.1111\/j.1525-1594.2006.00191.x","type":"journal-article","created":{"date-parts":[[2006,1,20]],"date-time":"2006-01-20T12:11:52Z","timestamp":1137759112000},"page":"101-105","source":"Crossref","is-referenced-by-count":5,"title":["Vasoconstrictor Administration During Cardiopulmonary Bypass Affects Acid\u2013Base Balance in Infants and Children"],"prefix":"10.1111","volume":"30","author":[{"given":"Koichi","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Sogawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Namura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Takekubo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010ichi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,20]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70116-8"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(96)01116-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002480-200209000-00011"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1594.2002.06915.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6918(03)00022-2"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)91219-L"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02160-3"},{"key":"e_1_2_6_9_2","first-page":"II","article-title":"Minimum hematocrit for normothermic cardiopulmonary bypass in dogs","volume":"96","author":"Cook DJ","year":"1997","journal-title":"Circulation"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1525-1594.2006.00191.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1525-1594.2006.00191.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T10:01:53Z","timestamp":1697104913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1525-1594.2006.00191.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,20]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["10.1111\/j.1525-1594.2006.00191.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1525-1594.2006.00191.x","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1,20]]}}}