{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:14:16Z","timestamp":1789143256685,"version":"build-2803163510"},"reference-count":62,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T00:00:00Z","timestamp":1312416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>\n                    (\n                    <jats:italic>Headache<\/jats:italic>\n                    2011;51:1254\u20101266)\n                  <\/jats:p>\n                  <jats:p>\n                    Neurostimulation for primary headaches is being increasingly utilized as a treatment modality. Use of neuromoduation has generated multiple case reports as well as some controlled studies. This article is the first of 2 systematic reviews of available data regarding neurostimulation for primary headache conditions. The pathophysiology, relative anatomy, theoretical mechanisms, and history of neurostimulation for primary headache are covered in this section, Part 1 of 2. The literature regarding\n                    <jats:italic>peripheral<\/jats:italic>\n                    neurostimulatory targets is also reviewed in Part 1. These\n                    <jats:italic>peripheral<\/jats:italic>\n                    targets include: percutaneous nerves, transcranial holocephalic, occipital nerves, auriculotemporal nerves, supraorbital nerves, cervical epidural, and sphenopalatine ganglia. Part 2 will focus on\n                    <jats:italic>central<\/jats:italic>\n                    stimulation, covering vagus nerve, and deep brain stimulation. Part 2 also contains an overall analysis of efficacy, safety, cost, patient selection, and suggestions for further study based on available evidence.\n                  <\/jats:p>","DOI":"10.1111\/j.1526-4610.2011.01966.x","type":"journal-article","created":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T16:34:31Z","timestamp":1312475671000},"page":"1254-1266","source":"Crossref","is-referenced-by-count":49,"title":["Neurostimulation for Primary Headache Disorders, Part 1: Pathophysiology and Anatomy, History of Neuromodulation in Headache Treatment, and Review of\n                    <i>Peripheral<\/i>\n                    Neuromodulation in Primary Headaches"],"prefix":"10.1111","volume":"51","author":[{"given":"Brian","family":"Jenkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart J.","family":"Tepper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,4]]},"reference":[{"key":"e_1_2_16_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg190"},{"key":"e_1_2_16_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.2.1001"},{"key":"e_1_2_16_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(97)00074-2"},{"key":"e_1_2_16_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.1999.19440579.x"},{"key":"e_1_2_16_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(01)00303-7"},{"key":"e_1_2_16_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf166"},{"key":"e_1_2_16_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01968.x"},{"key":"e_1_2_16_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)90125-U"},{"key":"e_1_2_16_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01501.x"},{"key":"e_1_2_16_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh416"},{"key":"e_1_2_16_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21994"},{"key":"e_1_2_16_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)02470-2"},{"key":"e_1_2_16_14_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.62.3.516"},{"key":"e_1_2_16_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04250-1"},{"key":"e_1_2_16_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01846.x"},{"key":"e_1_2_16_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70133-4"},{"key":"e_1_2_16_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq041"},{"key":"e_1_2_16_19_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3699.971"},{"key":"e_1_2_16_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2003.00567.x"},{"key":"e_1_2_16_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh022"},{"key":"e_1_2_16_22_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4609-05.2006"},{"key":"e_1_2_16_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.07.006"},{"key":"e_1_2_16_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jhmas\/XXXVII.1.51"},{"key":"e_1_2_16_25_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1938.1.5.405"},{"key":"e_1_2_16_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1990.tb05848.x"},{"key":"e_1_2_16_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70575-0"},{"key":"e_1_2_16_28_2","doi-asserted-by":"publisher","DOI":"10.1159\/000029599"},{"key":"e_1_2_16_29_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-196707000-00025"},{"key":"e_1_2_16_30_2","first-page":"223","article-title":"Pain suppression by peripheral nerve stimulation. 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