{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:58:55Z","timestamp":1789988335748,"version":"4.0.1"},"reference-count":51,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,8,3]],"date-time":"2011-08-03T00:00:00Z","timestamp":1312329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Headache"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>\n                    This article is the second of 2 articles reviewing neurostimulation for primary headaches. In Part 1, we described methods, pathophysiology and anatomy, and history of neuromodulation in the treatment of headache, as well as reviewing the literature on\n                    <jats:italic>peripheral<\/jats:italic>\n                    neuromodulation for primary headaches.\n                    <jats:italic>Peripheral<\/jats:italic>\n                    targets for stimulation include percutaneous nerves, transcranial holocephalic, occipital nerves, auriculotemporal nerves, supraorbital nerves, cervical epidural, and sphenopalatine ganglia. In Part 2, we describe available literature on\n                    <jats:italic>central<\/jats:italic>\n                    neuromodulation in primary headaches.\n                    <jats:italic>Central<\/jats:italic>\n                    stimulation targets include vagus nerve and deep brain structures. Part 2 also analyzes overall therapeutic efficacy, safety, cost, patient selection, and recommendations for further research of neurostimulation modalities based on available data.\n                  <\/jats:p>","DOI":"10.1111\/j.1526-4610.2011.01967.x","type":"journal-article","created":{"date-parts":[[2011,8,3]],"date-time":"2011-08-03T21:18:45Z","timestamp":1312406325000},"page":"1408-1418","source":"Crossref","is-referenced-by-count":31,"title":["Neurostimulation for Primary Headache Disorders: Part 2, Review of\n                    <i>Central<\/i>\n                    Neurostimulators for Primary Headache, Overall Therapeutic Efficacy, Safety, Cost, Patient Selection, and Future Research in Headache Neuromodulation"],"prefix":"10.1111","volume":"51","author":[{"given":"Brian","family":"Jenkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart J.","family":"Tepper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,3]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1998.tb01151.x"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00308-X"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2003.08.001"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00611.x"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-009-0073-3"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70575-0"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2007.11.003"},{"key":"e_1_2_9_9_2","first-page":"223","article-title":"Pain suppression by peripheral nerve stimulation. 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