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Twenty\u2010two symptomatic chronic heart failure patients were randomized to receive 800 mg oral magnesium oxide daily or placebo for 3 months. Data collected included large and small arterial elasticity\/compliance, hemodynamic parameters, exercise capacity, and quality\u2010of\u2010life score at baseline, 1 week, and 3 months. Patients who received magnesium had improved small arterial compliance at 3 months from baseline compared with placebo. This study suggests that chronic supplementation with oral magnesium is well tolerated and could improve endothelial function in symptomatic heart failure patients.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.1527-5299.2006.04692.x","type":"journal-article","created":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T08:39:17Z","timestamp":1170059957000},"page":"9-13","source":"Crossref","is-referenced-by-count":24,"title":["Acute and Chronic Oral Magnesium Supplementation: Effects on Endothelial Function, Exercise Capacity, and Quality of Life in Patients With Symptomatic Heart Failure"],"prefix":"10.1111","volume":"12","author":[{"given":"Johanna C.","family":"Fuentes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian A.","family":"Salmon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc 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