{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T20:57:12Z","timestamp":1771707432873,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,11,5]],"date-time":"2007-11-05T00:00:00Z","timestamp":1194220800000},"content-version":"vor","delay-in-days":6548,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsia"],"published-print":{"date-parts":[[1989,12]]},"abstract":"<jats:sec><jats:label\/><jats:p><jats:bold>Summary:<\/jats:bold>Forty patients with partial epilepsy that began before they were aged 3 years were recorded at the Centre Saint\u2010Paul between 1981 and 1986 with a follow\u2010up ranging from 1 year 9 months to 20 years. We analyzed the following data: age at onset, clinical features of seizures at onset and during the follow\u2010up period, ictal and interictal EEG features, etiologic circumstances, evolution of the epilepsy, and psychomotor development. The age of onset was mostly between 2 months and 2 years (more than two thirds of cases). Most had partial symptomatic epilepsy. In nine cases, epilepsy was preceded by febrile convulsions. Seizures at onset were of the following type (in order of decreasing occurrence): unilateral seizures, complex partial seizures, elementary partial seizures, and other seizures, often difficult to classify. A few patients with infantile spasms associated with focal or multifocal EEG abnormalities, differing from West's syndrome, were included in this study. We discuss the problem arising from the classification of infantile seizures and epilepsies.<\/jats:p><\/jats:sec><jats:sec><jats:title>R\u00c9SUM\u00c9<\/jats:title><jats:p>40 patients pr\u00e9sentant une \u00e9pilepsie partielle ayant d\u00e9but\u00e9 avant \u00e2ge de 3 ans ont \u00e9t\u00e9 examin\u00e9s au Centre Saint\u2010Paul entre 1980 et 1986, avec un suivi variant entre 1 an 9 mois et 20 ans. Les auteurs analysent les donn\u00e9es suivantes: \u00e2ge de d\u00e9but, la symptomatologie critique au d\u00e9but de \u00e9pilepsie et pendant la p\u00e9riode de suivi, les modifications EEG critiques et intercri\u2010tiques, les circonstances \u00e9tiologiques, \u00e9volution de \u00e9pilepsie et le d\u00e9veloppement psychomoteur. \u00e2ge de d\u00e9but se situait surtout entre 2 mois et 2 ans (plus des des cas). II s'agissait le plus souvent une \u00e9pilepsie partielle symptomatique. Dans 9 cas, \u00e9pilepsie avait \u00e9t\u00e9 pr\u00e9c\u00e9d\u00e9e par des convulsions f\u00e9briles.<\/jats:p><jats:p>Au d\u00e9but, les crises \u00e9taient du type suivant (par ordre de fr\u00e9quence d\u00e9croissante): crises unilaterales, crises partielles complexes, crises partielles \u00e9l\u00e9mentaires, autres types, souvent de classification difficile. Un petit nombre de patients avec spas\u2010mes infantiles associ\u00e9s \u00e0 des anomalies EEG focales ou multi\u2010focales, qui n'entraient pas dans le cadre un syndrome de West, ont \u00e9t\u00e9 inclus dans ce travail. Les auteurs discutent les problemes li\u00e9s \u00e0 la classification des crises et des \u00e9pilepsies de la petite enfance.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESUMEN<\/jats:title><jats:p>En el centro de Saint\u2010Paul y en el periodo transcurrido entre 1981 y 1986 con un seguimiento que oscilaba entre 17 meses y 20 anos se han estudiado 40 enfermos con epileps\u00eda parcial que hab\u00eda empezado antes de la edad de 3 a\u00f1os. Se ha analizado la informaci\u00f3n siguiente: edad de comienzo, contenido cl\u00ednico de los ataques al comienzo y durante el periodo de seguimiento, datos ictales e interictales del EEG, circunstancias etiol\u00f3gicas, y evoluti\u00f3n de la epilepsia y del desorden psicomotor. En de los casos, la edad de los casos oscilo entre dos meses y dos a\u00f1os. La mayor\u00eda de los casos tuvo epileps\u00eda parcial sintom\u00e1tica. En 9 casos la epileps\u00eda hab\u00eda sido precedida de convulsiones febriles. Los ataques al comienzo fueron de los tipos siguientes expresa\u2010dos en orden decreciente: ataques unilaterales, ataques parciales complejos, ataques parciales elementales y otro tipo de ataques frecuentemente de clasificaci\u00f3n dificil. Un grupo peque\u00f1o de enfermos con espasmos infantiles asociados a anomal\u00edas focales o multifocales en el EEG (diferentes del s\u00edndrome de West) han sido incluidos en este estudio. Los autores discuten el problema que surge en la clasificaci\u00f3n de ataques infantiles y epileps\u00edas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1528-1157.1989.tb05343.x","type":"journal-article","created":{"date-parts":[[2007,11,5]],"date-time":"2007-11-05T17:48:38Z","timestamp":1194284918000},"page":"807-812","source":"Crossref","is-referenced-by-count":51,"title":["Partial Epilepsies in Infancy: A Study of 40 Cases"],"prefix":"10.1111","volume":"30","author":[{"given":"C.","family":"Dravet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Catani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bureau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Roger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,11,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1469-8749.1982.tb13620.x","article-title":"Atypical benign partial epilepsy of childhood","volume":"24","author":"Aicardi J.","year":"1982","journal-title":"Dev Med Child Neurol"},{"key":"e_1_2_1_3_1","author":"Boniver C.","journal-title":"Partial cryptogenic epilepsy of the first year of life: electroclinical study of 9 cases"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1984.tb04467.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1978.tb05013.x"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1981.tb06159.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1985.tb05417.x"},{"key":"e_1_2_1_8_1","first-page":"245","article-title":"Epilepsies of the first two years of life: clinical\u2010prognostic study of 284 cases","volume":"18","author":"Curatolo O.","year":"1980","journal-title":"Acta Med Rom"},{"key":"e_1_2_1_9_1","first-page":"137","volume-title":"Epileptic syndromes in infancy, childhood and adolescence.","author":"Dalla Bernardina B.","year":"1985"},{"key":"e_1_2_1_10_1","first-page":"145","article-title":"Aspetti clinici ed evolutivi a medio termine delle crisi parziali dei primi due anni","volume":"22","author":"Cagno L.","year":"1978","journal-title":"Boll Lega It Epil"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1970.tb03871.x"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(83)80076-X"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1988.tb05095.x"}],"container-title":["Epilepsia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1528-1157.1989.tb05343.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1528-1157.1989.tb05343.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,18]],"date-time":"2024-02-18T21:27:32Z","timestamp":1708291652000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1528-1157.1989.tb05343.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,12]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1989,12]]}},"alternative-id":["10.1111\/j.1528-1157.1989.tb05343.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1528-1157.1989.tb05343.x","archive":["Portico"],"relation":{},"ISSN":["0013-9580","1528-1167"],"issn-type":[{"value":"0013-9580","type":"print"},{"value":"1528-1167","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,12]]}}}