{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T12:19:37Z","timestamp":1780661977414,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T00:00:00Z","timestamp":1318809600000},"content-version":"vor","delay-in-days":46,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>Carpal tunnel syndrome (CTS) is one of the most common upper limb compression neuropathies. In only 50% of cases it is possible to identify a cause. Our objective was to determine the role of glucose metabolism abnormalities in idiopathic CTS. We identified 117 patients with idiopathic moderate or severe CTS and 128 controls. In all we evaluated glucose and insulin levels at fasting and after 2\u2010h oral glucose tolerance test (2h\u2010OGTT). In addition we determined insulin resistance (IR). Following OGTT the prevalence of glucose metabolism abnormalities was significantly higher in the CTS group (p = 0.001). IR was documented in 80% of patients, of whom 45% had impaired glucose tolerance, 14% newly diagnosed diabetes mellitus, and 20% IR only. Waist circumference and body mass index were also significantly increased in the CTS group. In this study, we focused on evidence that pre\u2010diabetes may represent a risk factor for CTS. We proposed to determine IR as a rule in all patients with idiopathic CTS.<\/jats:p>","DOI":"10.1111\/j.1529-8027.2011.00344.x","type":"journal-article","created":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T11:59:27Z","timestamp":1318852767000},"page":"186-190","source":"Crossref","is-referenced-by-count":26,"title":["Insulin resistance increases risk of carpal tunnel syndrome: a case\u2010control study"],"prefix":"10.1111","volume":"16","author":[{"given":"Massimiliano","family":"Plastino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonietta","family":"Fava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colica","family":"Carmela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"De Bartolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Ermio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Cristiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ettore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovico","family":"Abenavoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Bosco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,17]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"1390","article-title":"Practice parameter for electrodiagnostic studies in carpal tunnel syndrome: summary statement.","volume":"69","author":"American Association of Electrodiagnostic Medicine, American of Neurology, American Academy of Physical Medicine and Rehabilitation","year":"1993","journal-title":"Muscle Nerve"},{"key":"e_1_2_5_3_1","first-page":"6","article-title":"Carpal tunnel syndrome.","volume":"77","author":"Aroori S","year":"2008","journal-title":"Ulster Med J"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.2.153"},{"key":"e_1_2_5_5_1","first-page":"123","article-title":"Prevalence and severity of carpal tunnel syndrome during pregnancy.","volume":"45","author":"Bahrami MH","year":"2005","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20408"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.03.017"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301536200"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.634"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753193408087119"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.4.817"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-198907000-00002"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(87)90063-1"},{"key":"e_1_2_5_14_1","first-page":"833","article-title":"Follow\u2010up report on the diagnosis of diabetes mellitus.","volume":"52","author":"Genuth S","year":"2003","journal-title":"Diabetes Care"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-0939"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp013018"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00280883"},{"key":"e_1_2_5_18_1","first-page":"189","article-title":"CTS: carpal tunnel syndrome, the facts and myths.","volume":"95","author":"Melhorn JM","year":"1994","journal-title":"Kans Med"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.12.2867"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e31815a3956"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(03)00102-1"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.60.1.108"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.7.1783"}],"container-title":["Journal of the Peripheral Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1529-8027.2011.00344.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1529-8027.2011.00344.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T01:40:06Z","timestamp":1697334006000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1529-8027.2011.00344.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1111\/j.1529-8027.2011.00344.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1529-8027.2011.00344.x","archive":["Portico"],"relation":{},"ISSN":["1085-9489","1529-8027"],"issn-type":[{"value":"1085-9489","type":"print"},{"value":"1529-8027","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}