{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:03:08Z","timestamp":1771462988764,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,4,6]],"date-time":"2012-04-06T00:00:00Z","timestamp":1333670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Little is known about the effects of low levels of maternal alcohol intake on the neuropsychological development of the child. This study is part of an ongoing investigation on maternal drinking and presents data on demographic variables, maternal alcohol use, and birth outcomes from that study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The sample comprised 2,264 women from a Swedish antenatal clinic. Retrospective self\u2010report data were collected on alcohol consumption before and during pregnancy, using the Alcohol Use Disorders Identification Test (AUDIT), and on nicotine use. Specific alcohol biomarkers for excessive drinking, carbohydrate\u2010deficient transferrin (CDT) in serum and phosphatidylethanol (PEth) in whole blood, were determined during mid\u2010pregnancy in a subsample of the women. Data on labor and early characteristics of the child were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Before pregnancy, 89% of the women regularly consumed alcohol and 49% reported occasional or frequent binge drinking. Nicotine was used by 15% before and by 5% during pregnancy. During pregnancy, 12% continued using alcohol and 5% also admitted binge drinking. However, all alcohol biomarker values were below the reporting limits (CDT\u00a0\u2264\u00a01.7% disialotransferrin; total PEth\u00a0&lt;\u00a00.1\u00a0\u03bcmol\/L). Self\u2010reported drinking during pregnancy was associated with a higher AUDIT score before pregnancy, nicotine use at the time of the first prenatal visit, older age, and previous legal abortions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The AUDIT questionnaire and 2 specific alcohol biomarkers were used in routine maternity care to collect information about drinking during pregnancy and thereby to identify children at risk for alcohol\u2010related complications. While the AUDIT results suggested that a significant number of women continued using alcohol during pregnancy, implying a risk for fetal disorders, the biomarkers showed negative test values thus indicating only modest drinking levels.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1530-0277.2012.01783.x","type":"journal-article","created":{"date-parts":[[2012,4,6]],"date-time":"2012-04-06T18:17:29Z","timestamp":1333736249000},"page":"1779-1786","source":"Crossref","is-referenced-by-count":44,"title":["Alcohol Consumption Among Pregnant Women in a Swedish Sample and Its Effects on the Newborn Outcomes"],"prefix":"10.1111","volume":"36","author":[{"given":"Erika","family":"Comasco","sequence":"first","affiliation":[{"name":"Department of Neuroscience Unit of Pharmacology Uppsala University Uppsala Sweden"},{"name":"Center for Clinical Research V\u00e4ster\u00e5s V\u00e4ster\u00e5s Central Hospital Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunilla","family":"Hallberg","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Unit of Obstetrics and Gynecology Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Helander","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Karolinska Institutet and Karolinska University Laboratory Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Oreland","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Unit of Pharmacology Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viveka","family":"Sundelin\u2010Wahlsten","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Unit of Child and Adolescent Psychiatry Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2006.00055.x"},{"key":"e_1_2_6_3_1","unstructured":"BaborTF Higgins\u2010BiddleJC SaundersJB MonteiroMG(1991)The Alcohol Use Disorders Identification Test. 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