{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:57:19Z","timestamp":1760061439925},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Alcohol dependence is associated with increased mortality, but it is not clear whether certain laboratory abnormalities on admission predict premature death in discharged alcoholic patients. We examined total deaths and alcohol\u2010attributable deaths among discharged alcohol\u2010dependent patients in <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>orea, and the associated risk factors including laboratory abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The subjects consisted of 442 patients who were admitted for alcohol dependence to a general hospital located in <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eoul, <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>orea from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1989 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2006. At the end of 2009, the risk of death among the discharged alcohol\u2010dependent patients was compared with that of the general population of <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>orea by calculating standardized mortality ratios. Cox proportional hazards regression models were used to analyze the risk factors for total deaths and alcohol\u2010attributable deaths in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010nine percent (127\/442) of the discharged alcoholic patients died during the study period. Mortality among these patients was 6.67 times higher than in the <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>orean population as a whole (7.12 times for men and 2.62 times for women). The most common causes of death were alcoholic liver disease and unspecified liver cirrhosis. Recurrent admission and low albumin level at admission were independently associated with both all causes and alcohol\u2010attributable mortality. High bilirubin level at admission was independently associated with alcohol\u2010attributable mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These observations indicate a high risk of death in discharged alcohol\u2010dependent patients, particularly those who are repeatedly admitted to psychiatric wards or who yield abnormal laboratory findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1530-0277.2012.01943.x","type":"journal-article","created":{"date-parts":[[2012,10,11]],"date-time":"2012-10-11T11:02:17Z","timestamp":1349953337000},"page":"270-275","source":"Crossref","is-referenced-by-count":6,"title":["Clinical and Laboratory Predictors of All Causes Deaths and Alcohol\u2010Attributable Deaths Among Discharged Alcohol\u2010Dependent Patients"],"prefix":"10.1111","volume":"37","author":[{"given":"Subin","family":"Park","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry  Seoul National University Hospital Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Pyo","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry  Asan Medical Center Ulsan University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry  Asan Medical Center Ulsan University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Hee","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Psychiatry  Asan Medical Center Ulsan University College of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agn099"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1984.tb01228.x"},{"key":"e_1_2_5_4_1","unstructured":"Centers for Disease Control and Prevention(2008)Alcohol Related Disease Impact (ARDI) application. 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