{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:44:25Z","timestamp":1772012665593,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T00:00:00Z","timestamp":1309392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>\n                    <jats:bold>OBJECTIVES:<\/jats:bold>\n                    To determine the diagnostic yield of Holter monitoring in very old adults (\u226580) with syncope.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>DESIGN:<\/jats:bold>\n                    A Holter study was considered diagnostic if the arrhythmia explained syncope (atrioventricular (AV) block, sinus node dysfunction, atrial fibrillation with severe bradycardia or tachycardia, supraventricular or ventricular tachycardia).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>SETTING:<\/jats:bold>\n                    A tertiary care center in Switzerland over a period of 10 years.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>PARTICIPANTS:<\/jats:bold>\n                    Four hundred seventy\u2010five Holter studies were performed in individuals aged 80 and older (median age 84, 65% female, mean left ventricular ejection fraction (LVEF) 0.56 \u00b1 0.1%).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>MEASUREMENTS AND RESULTS:<\/jats:bold>\n                    Fifty\u2010three Holter studies (11%) were diagnostic. The detected arrhythmias were AV block (n=13), sinus node dysfunction (n=13), binodal disease (n=2), atrial fibrillation with slow or rapid ventricular response (n=21), ventricular tachycardia (n=3) and supraventricular tachycardia (n=1). Forty participants (8%) received a pacemaker, and one received an implantable cardioverter\u2010defibrillator because of the results of Holter monitoring. The yield of Holter monitoring was significantly greater (all\n                    <jats:italic>P<\/jats:italic>\n                    &lt;.01) in the presence of heart disease (17%) and low LVEF (22%), in men (17%) and in participants aged 90 and older (20%). Heart disease (odds ratio (OR)=3.2, 95% confidence interval (CI)=1.7\u20136.1), male sex (OR=2.1, 95% CI=1.1\u20133.8), and aged 90 and older (OR=2.4, 95% CI=1.2\u20135.1) remained independent predictors for a high diagnostic yield of Holter monitoring. Furthermore, Holter monitoring was helpful in excluding arrhythmias as a cause of syncope in an additional 10% of cases.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>CONCLUSION:<\/jats:bold>\n                    The diagnostic value of Holter monitoring in participants aged 80 and older with syncope was 11.2%. Its yield was higher in men and in the presence of structural heart disease and was 20% in individuals aged 90 and older.\n                  <\/jats:p>","DOI":"10.1111\/j.1532-5415.2011.03486.x","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T15:28:29Z","timestamp":1309447709000},"page":"1293-1298","source":"Crossref","is-referenced-by-count":15,"title":["Holter Monitoring in Syncope: Diagnostic Yield in Octogenarians"],"prefix":"10.1111","volume":"59","author":[{"given":"Michael","family":"K\u00fchne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beat","family":"Schaer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Sticherling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Osswald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,30]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1001\/jama.1982.03330100023024","article-title":"Patients with syncope admitted to medical intensive care units","volume":"248","author":"Silverstein MD","year":"1982","journal-title":"JAMA"},{"key":"e_1_2_8_3_2","first-page":"1280","article-title":"Management of syncope in adults","volume":"83","author":"Chen LY","year":"2008","journal-title":"An update"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012407"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90261-M"},{"key":"e_1_2_8_6_2","first-page":"18","article-title":"Role of early symptoms in assessment of syncope in elderly people","volume":"57","author":"Galizia G","year":"2009","journal-title":"Results from the Italian Group for the Study of Syncope in the Elderly"},{"key":"e_1_2_8_7_2","first-page":"771","article-title":"Holter monitoring for syncope","volume":"100","author":"Kuhne M","year":"2007","journal-title":"Diagnostic yield in different patient groups and impact on device implantation"},{"key":"e_1_2_8_8_2","first-page":"2539","article-title":"Guidelines for the Diagnosis and Management of Syncope reviewed by Angel Moya, MD, FESC, Chair of the Guideline Taskforce with J. Taylor, MPhil","volume":"30","author":"The European Society of Cardiology","year":"2009","journal-title":"Eur Heart J"},{"key":"e_1_2_8_9_2","first-page":"2631","article-title":"Guidelines for the Diagnosis and Management of Syncope (version 2009)","volume":"30","author":"Moya A","year":"2009","journal-title":"The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC)"},{"key":"e_1_2_8_10_2","first-page":"473","article-title":"AHA\/ACCF scientific statement on the evaluation of syncope","volume":"47","author":"Strickberger SA","year":"2006","journal-title":"From the American Heart Association Councils on Clinical Cardiology, Cardiovascular Nursing, Cardiovascular Disease in the Young, and Stroke, and the Quality of Care and Outcomes Research Interdisciplinary Working Group; and the American College of Cardiology Foundation in Collaboration with the Heart Rhythm Society"},{"key":"e_1_2_8_11_2","first-page":"2256","article-title":"Guidelines for Cardiac Pacing and Cardiac Resynchronization Therapy","volume":"28","author":"Vardas PE","year":"2007","journal-title":"The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association"},{"key":"e_1_2_8_12_2","first-page":"241","article-title":"Predictors of arrhythmic events during second day monitoring in patients with normal first day Holter recordings","volume":"57","author":"Arya A","year":"2005","journal-title":"Indian Heart J"},{"key":"e_1_2_8_13_2","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1001\/archinte.1990.00390170103022","article-title":"The duration of Holter monitoring in patients with syncope. Is 24 hours enough?","volume":"150","author":"Bass EB","year":"1990","journal-title":"Arch Intern Med"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00233-X"},{"key":"e_1_2_8_15_2","first-page":"41","article-title":"Syncope","volume":"4","author":"Subbiah R","year":"2008","journal-title":"Review of monitoring modalities"},{"key":"e_1_2_8_16_2","first-page":"477","article-title":"Implantable loop recorder for recurrent syncope","volume":"10","author":"Pierre B","year":"2008","journal-title":"Influence of cardiac conduction abnormalities showing up on resting electrocardiogram and of underlying cardiac disease on follow-up developments"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20342"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup097"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1532-5415.2011.03486.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1532-5415.2011.03486.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T19:00:49Z","timestamp":1762196449000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/j.1532-5415.2011.03486.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,30]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1111\/j.1532-5415.2011.03486.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1532-5415.2011.03486.x","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,30]]}}}