{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:25:34Z","timestamp":1790029534885,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T00:00:00Z","timestamp":1351555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify the determinants of antihypertensive medication adherence in community\u2010living elderly adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Longitudinal observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>\n                      Population\u2010based health survey in the province of\n                      <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>\n                      uebec,\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      anada.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Data from a representative sample (N\u00a0=\u00a02,811) of community\u2010dwelling adults in Quebec aged 65 and older participating in the \u00c9tude sur la Sant\u00e9 des A\u00een\u00e9s study. The final study sample analyzed consisted of 926 participants taking antihypertensive drugs during the 2\u00a0years of the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Adherence to antihypertensive medication was measured using days of supply obtained during a specified time period. Depression and anxiety disorders were assessed using\n                      <jats:italic>\n                        <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\n                        iagnostic and\n                        <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                        tatistical\n                        <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                        anual of\n                        <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                        ental\n                        <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>\n                        isorders,\n                        <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>\n                        ourth\n                        <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                        dition\n                      <\/jats:italic>\n                      , criteria, and physical health status was measured using the\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      harlson\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      omorbidity\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      ndex. Other factors considered were age, education, marital status, annual family income, and number of antihypertensive drugs that participants used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean antihypertensive proportion (percentage) of days supplied in was 92.5% in Year 1 and 59.4% in Year 2. The presence of depression and anxiety disorders and the number of antihypertensive medications significantly predicted medication adherence. The sex by depression and anxiety disorders interaction term was significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adherence to antihypertensive medication was significantly associated with depression and anxiety disorders in men but not women. The treatment of depression and anxiety disorders in individuals with hypertension may be helpful in improving medication adherence rates and healthcare outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1532-5415.2012.04239.x","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T14:02:59Z","timestamp":1351605779000},"page":"2297-2301","source":"Crossref","is-referenced-by-count":48,"title":["Association Between Depressive and Anxiety Disorders and Adherence to Antihypertensive Medication in Community\u2010Living Elderly Adults"],"prefix":"10.1111","volume":"60","author":[{"given":"Lia","family":"Gentil","sequence":"first","affiliation":[{"name":"Sant\u00e9 Communautaire University of Sherbrook Longueuil Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen Maria","family":"Vasiliadis","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Communautaire University of Sherbrook Longueuil Quebec Canada"},{"name":"Research Center Charles LeMoyne Hospital Longueuil Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Pr\u00e9ville","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Communautaire University of Sherbrook Longueuil Quebec Canada"},{"name":"Research Center Charles LeMoyne Hospital Longueuil Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Boss\u00e9","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Communautaire University of Sherbrook Longueuil Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamal","family":"Berbiche","sequence":"additional","affiliation":[{"name":"Research Center Charles LeMoyne Hospital Longueuil Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,30]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Public Health Agency of Canada.Report from the Canadian Chronic Disease Surveillance System: Hypertension in Canada 2010.Ottawa ON Canada:Public Health Agency of Canada[on\u2010line]. 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