{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T10:02:41Z","timestamp":1785578561483,"version":"3.56.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,4,5]],"date-time":"2006-04-05T00:00:00Z","timestamp":1144195200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold>Objective\u2014<\/jats:bold>To describe outcome after thyroidectomy in hyperthyroid cats, with emphasis on peri\u2010 and postsurgical complications and recurrence.<\/jats:p><jats:p><jats:bold>Study Design\u2014<\/jats:bold>Retrospective study.<\/jats:p><jats:p><jats:bold>Animals\u2014<\/jats:bold>One hundred and one hyperthyroid cats.<\/jats:p><jats:p><jats:bold>Methods\u2014<\/jats:bold>Diagnostic work\u2010up included preoperative measurement of plasma calcium, sodium, potassium, urea, and creatinine concentrations, and thyroid scintigraphy. A modified intracapsular dissection technique was performed. Postoperatively, parathyroid gland function was evaluated by measuring plasma calcium concentration several times daily. Outcome was obtained by standard telephone questionnaire.<\/jats:p><jats:p><jats:bold>Results\u2014<\/jats:bold>Thyroid scintigraphy revealed ectopic hyperplastic thyroid tissue (EHTT) in 9 cats. Preoperatively, 29 of 91 cats had hypokalemia. Two cats died within 3 days after surgery and 5 of 86 cats developed postoperative transient hypocalcemia. On histologic examination, thyroid carcinoma was identified in 3 of 88 cats. Hyperthyroidism recurred in 5 cats between 3 and 59 months; 4 of these cats had EHTT preoperatively. The difference in recurrence rate between hyperthyroid cats with and without EHTT was significant (<jats:italic>P<\/jats:italic>&lt;.001).<\/jats:p><jats:p><jats:bold>Conclusion\u2014<\/jats:bold>Complications were uncommon after thyroidectomy performed by an experienced surgeon when combined with an anesthetic regimen associated with minimal adverse cardiovascular effects. Hyperthyroid cats with EHTT had a significantly higher chance of recurrence.<\/jats:p><jats:p><jats:bold>Clinical Relevance\u2014<\/jats:bold>Thyroidectomy is associated with a low incidence of surgical complications and is an effective treatment for hyperthyroid cats when radioactive iodine therapy is not available. Preoperative thyroid scintigraphy is advised. Surgery is not recommended when EHTT is present, because of a higher chance of developing recurrent disease.<\/jats:p>","DOI":"10.1111\/j.1532-950x.2006.00146.x","type":"journal-article","created":{"date-parts":[[2006,4,5]],"date-time":"2006-04-05T14:29:39Z","timestamp":1144247379000},"page":"287-293","source":"Crossref","is-referenced-by-count":76,"title":["Results of Thyroidectomy in 101 Cats with Hyperthyroidism"],"prefix":"10.1111","volume":"35","author":[{"given":"ELAINE C.","family":"NAAN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOLLE","family":"KIRPENSTEIJN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HANS S.","family":"KOOISTRA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARIJKE E.","family":"PEETERS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,4,5]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"91","volume-title":"Canine and Feline Endocrinology and Reproduction","author":"Feldman EC","year":"1987"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2002.0177"},{"key":"e_1_2_6_4_2","first-page":"518","volume-title":"Small Animal Surgery","author":"Fossum TW","year":"2002"},{"key":"e_1_2_6_5_2","first-page":"103","article-title":"Feline hyperthyroidism","volume":"183","author":"Peterson ME","year":"1983","journal-title":"pretreatment clinical and laboratory evaluation of 131 cases"},{"key":"e_1_2_6_6_2","first-page":"52","article-title":"Congestive heart failure associated with hyperthyroidism in cats","volume":"188","author":"Jacobs G","year":"1986","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(94)50060-3"},{"key":"e_1_2_6_8_2","first-page":"963","article-title":"Feline hyperthyroidism","volume":"31","author":"Mooney CT","year":"2001","journal-title":"diagnostics and therapeutics"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(02)00023-2"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1989.tb01107.x"},{"key":"e_1_2_6_11_2","first-page":"433","article-title":"Recurrence of hyperthyroidism after thyroidectomy in cats","volume":"26","author":"Swalec KM","year":"1990","journal-title":"J Am Animal Hosp Assoc"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-612X(99)90201-2"},{"key":"e_1_2_6_13_2","first-page":"362","article-title":"Feline Thyroidectomy","volume":"16","author":"Flanders JA","year":"1987","journal-title":"a comparison of postoperative hypocalcemia associated with three different surgical techniques"},{"key":"e_1_2_6_14_2","first-page":"1700","volume-title":"Textbook of Small Animal Surgery","author":"Ehrhart N","year":"2002"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.2460\/ajvr.1991.52.08.1336","article-title":"Functional analysis of ectopic parathyroid activity in cats","volume":"52","author":"Flanders JA","year":"1991","journal-title":"Am J Vet Res"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(94)50062-7"},{"key":"e_1_2_6_17_2","first-page":"5","article-title":"Investigations of the effects of hyperthyroidism on renal function in cats","volume":"61","author":"Adams WH","year":"1997","journal-title":"Can J Vet Res"},{"key":"e_1_2_6_18_2","volume-title":"Kirk's Current Veterinary Therapy","author":"DiBartola SP","year":"2000"},{"key":"e_1_2_6_19_2","first-page":"52","article-title":"Hypertrophic cardiomyopathy and hyperthyroidism in the cat","volume":"185","author":"Liu S","year":"1984","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_20_2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2460\/javma.1994.205.01.65","article-title":"Acute onset of hypokalemia and muscular weakness in four hyperthyroid cats","volume":"205","author":"Nemzek JA","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_21_2","first-page":"612","volume-title":"Clinical Anesthesiology","author":"Morgan GE","year":"2002"},{"key":"e_1_2_6_22_2","first-page":"324","volume-title":"Veterinary Anesthesia","author":"Hall LW","year":"1991"},{"key":"e_1_2_6_23_2","first-page":"885","article-title":"A review of the physiological effects of \u03b12\u2010agonists related to the clinical use of medetomidine in small animal practice","volume":"44","author":"Sinclair MD","year":"2003","journal-title":"Can Vet J"},{"key":"e_1_2_6_24_2","first-page":"359","article-title":"Thyroid carcinoma causing hyperthyroidism in cats","volume":"193","author":"Turrel JM","year":"1988","journal-title":"14 cases (1981\u20131986)"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(94)50061-5"},{"key":"e_1_2_6_26_2","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.2460\/javma.1995.207.08.1055","article-title":"Response to high\u2010dose radioactive iodine administration in cats with thyroid carcinoma that had previously undergone surgery","volume":"207","author":"Guptill L","year":"1995","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-0105-6_3"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2002.tb01021.x"},{"key":"e_1_2_6_29_2","first-page":"554","article-title":"Radioactive iodine therapy in cats with hyperthyroidism","volume":"184","author":"Turrel JM","year":"1984","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_6_30_2","first-page":"1038","article-title":"Serum thyroxine concentrations after radioactive iodine therapy in cats with hyperthyroidism","volume":"188","author":"Meric SM","year":"1986","journal-title":"J Am Vet Assoc"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1988.tb02812.x"},{"key":"e_1_2_6_32_2","first-page":"1141","article-title":"Beta\u2010blockers compared with antithyroid drugs as preoperative treatment in hyperthyroidism","volume":"98","author":"Lennquist S","year":"1985","journal-title":"drug tolerance, complications, and postoperative thyroid function"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1990.tb03104.x"},{"key":"e_1_2_6_34_2","volume-title":"Cancer in Dogs and Cats","author":"Waters CB","year":"1998"},{"key":"e_1_2_6_35_2","first-page":"767","article-title":"Recommendations on sampling, transport and storage for the determination of concentration of ionized calcium in whole blood, plasma and serum","volume":"29","author":"Boink ABTJ","year":"1991","journal-title":"Eur J Clin Chem Clin Biochem"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1532-950X.2006.00146.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1532-950X.2006.00146.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T16:01:06Z","timestamp":1706976066000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1532-950X.2006.00146.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1111\/j.1532-950X.2006.00146.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1532-950x.2006.00146.x","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}