{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:39:01Z","timestamp":1770219541666,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T00:00:00Z","timestamp":1217462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p><jats:bold>Objective\u2014<\/jats:bold> To characterize the clinical signs, diagnostic and surgical findings, and outcome of dogs with idiopathic sterile pyogranulomatous inflammation (ISP) of epidural fat causing spinal cord compression.<\/jats:p><jats:p><jats:bold>Study Design\u2014<\/jats:bold> Retrospective study.<\/jats:p><jats:p><jats:bold>Animals\u2014<\/jats:bold> Dogs (n=5).<\/jats:p><jats:p><jats:bold>Methods\u2014<\/jats:bold> Dogs with epidural ISP (2002\u20132006) were identified retrospectively. Inclusion criteria were neurologic examination, myelography, and definitive diagnosis of ISP confirmed by surgery and histopathologic examination of epidural spinal cord compressive tissue.<\/jats:p><jats:p><jats:bold>Results\u2014<\/jats:bold> The most common clinical sign was paraparesis\/paraplegia. No abnormalities were detected by laboratory testing or survey spine radiographs. On myelography, extradural spinal cord compressions were focal (dogs 1, 3, and 5) or multifocal (dogs 2 and 4). Surgical decompression of the spinal cord was completed by hemilaminectomy. Epidural fat collected surgically had pyogranulomatous inflammation of unknown cause and was histologically similar to subcutaneous ISP. All dogs had good long\u2010term neurologic outcome (10\u201345 months follow\u2010up). Some dogs had episodes of ISP at other sites before or after surgical treatment of epidural ISP, suggesting there may be a systemic form of ISP.<\/jats:p><jats:p><jats:bold>Conclusion\u2014<\/jats:bold> Epidural ISP may cause a spinal cord compressive lesion in Miniature Dachshunds, which can be treated by surgical decompression of the spinal cord with or without administration of adjunctive steroids.<\/jats:p><jats:p><jats:bold>Clinical Relevance\u2014<\/jats:bold> Epidural ISP should be considered as a possible cause of thoracolumbar myelopathy for Miniature Dachshunds.<\/jats:p>","DOI":"10.1111\/j.1532-950x.2008.00436.x","type":"journal-article","created":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T21:15:28Z","timestamp":1217538928000},"page":"594-601","source":"Crossref","is-referenced-by-count":16,"title":["Epidural Idiopathic Sterile Pyogranulomatous Inflammation Causing Spinal Cord Compressive Injury in Five Miniature Dachshunds"],"prefix":"10.1111","volume":"37","author":[{"given":"TAKESHI","family":"AIKAWA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YUKI","family":"YOSHIGAE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHINICHI","family":"KANAZONO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,31]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1136","volume-title":"Miller and Kirk's Small Animal Dermatology","author":"Scott DW","year":"2001"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2003.tb00104.x"},{"key":"e_1_2_6_4_2","first-page":"673","article-title":"Canine diskospondylitis","volume":"97","author":"Betbeze C","year":"2002","journal-title":"its etiology, diagnosis, and treatment"},{"key":"e_1_2_6_5_2","first-page":"268","article-title":"Signalment and clinical features of diskospondylitis in dogs","volume":"277","author":"Burkert BA","year":"2005","journal-title":"513 cases (1980\u20132001)"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2000.tb01467.x"},{"key":"e_1_2_6_7_2","first-page":"197","article-title":"Neuroimaging of tuberculous myelitis","volume":"16","author":"Wasey M","year":"2006","journal-title":"analysis of ten cases and review of literature"},{"key":"e_1_2_6_8_2","first-page":"124","article-title":"Spinal tuberculosis","volume":"36","author":"Le Page L","year":"2006","journal-title":"a longitudinal study with clinical, laboratory, and imaging outcomes"},{"key":"e_1_2_6_9_2","first-page":"297","article-title":"Spinal tuberculosis mimicking malignancy","volume":"74","author":"Khattry N","year":"2007","journal-title":"atypical imaging features"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.0669-06"},{"key":"e_1_2_6_11_2","first-page":"842","volume-title":"Textbook of Veterinary Internal Medicine","author":"Ettinger SJ","year":"2005"},{"key":"e_1_2_6_12_2","first-page":"175","article-title":"Spinal epidural empyema in seven dogs","volume":"35","author":"Lavey JA","year":"2006","journal-title":"Vet Surg"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1055\/s-0038-1632944","article-title":"Spinal epidural abscess in a juvenile dog","volume":"18","author":"Schmiedt CW","year":"2005","journal-title":"Vet Comp Orthop Traumatol"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2005.00425.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.68.95"}],"container-title":["Veterinary Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1532-950X.2008.00436.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1532-950X.2008.00436.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T17:32:01Z","timestamp":1697131921000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1532-950X.2008.00436.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,31]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1111\/j.1532-950X.2008.00436.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1532-950x.2008.00436.x","archive":["Portico"],"relation":{},"ISSN":["0161-3499","1532-950X"],"issn-type":[{"value":"0161-3499","type":"print"},{"value":"1532-950X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,31]]}}}