{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:09:37Z","timestamp":1789387777722,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T00:00:00Z","timestamp":1304380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Surgery"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold>To characterize pulmonary gas exchange and arterial lactate in horses with gastrointestinal disease undergoing anesthesia, compared with elective surgical horses, and to correlate these variables with postoperative complications and mortality.<\/jats:p><jats:p><jats:bold>Study Design:<\/jats:bold>Prospective clinical study.<\/jats:p><jats:p><jats:bold>Animals:<\/jats:bold>Horses undergoing emergency laparotomy for acute intestinal disease (n=50) and healthy horses undergoing elective surgery in dorsal recumbency (n=20).<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold>Arterial blood gas analysis was performed at predetermined intervals on horses undergoing a standardized anesthetic protocol. Alveolar\u2013arterial oxygen gradient was calculated. Predictive factors for postoperative complications and death in colic horses were determined.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold>Arterial oxygen tension (P<jats:sub>a<\/jats:sub>O<jats:sub>2<\/jats:sub>) varied widely among horses in both groups. P<jats:sub>a<\/jats:sub>O<jats:sub>2<\/jats:sub>significantly increased in the colic group after exteriorization of the ascending colon. P<jats:sub>a<\/jats:sub>O<jats:sub>2<\/jats:sub>and alveolar\u2013arterial oxygen gradient were not significantly different between groups, and neither were correlated with horse outcome. Arterial lactate in recovery \u22655\u2003mmol\/L was associated with a 2.25 times greater relative risk of complications and lactate \u22657\u2003mmol\/L was associated with a 10.5 times higher relative risk of death.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold>Colic horses in this population were not more likely to be hypoxemic than elective horses, nor was gas exchange impaired to a greater degree in colic horses relative to controls. Arterial lactate sampled immediately after anesthetic recovery was predictive for postoperative complications and death.<\/jats:p>","DOI":"10.1111\/j.1532-950x.2011.00840.x","type":"journal-article","created":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T16:07:58Z","timestamp":1304438878000},"page":"601-609","source":"Crossref","is-referenced-by-count":30,"title":["Pulmonary Gas Exchange and Plasma Lactate in Horses with Gastrointestinal Disease Undergoing Emergency Exploratory Laparotomy: A Comparison with an Elective Surgery Horse Population"],"prefix":"10.1111","volume":"40","author":[{"given":"Annette M.","family":"McCoy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen S.","family":"Hackett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann 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