{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:55:15Z","timestamp":1780631715427,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,1,19]],"date-time":"2005-01-19T00:00:00Z","timestamp":1106092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:p><jats:bold>BACKGROUND:\u2002<\/jats:bold> Optimizing product quality is a current focus in cord blood banking. This study evaluates the role of selected donor\u2010 and collection\u2010related variables.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:\u2002<\/jats:bold> Retrospective review was performed of cord blood units (CBUs) collected ex utero between February 1, 2000, and February 28, 2002. Preprocessing volume and total nucleated cell (TNC) counts and postprocessing CD34 cell counts were used as product quality indicators.<\/jats:p><jats:p><jats:bold>RESULTS:\u2002<\/jats:bold> Of 2084 CBUs, volume determinations and TNC counts were performed on 1628 and CD34+ counts on 1124 CBUs. Mean volume and TNC and CD34+ counts were 85.2\u2003mL, 118.9\u2003\u00d7\u200310<jats:sup>7<\/jats:sup>, and 5.2\u2003\u00d7\u200310<jats:sup>6<\/jats:sup>, respectively. In univariate analysis, placental weight of greater than 500\u2003g and meconium in amniotic fluid correlated with better volume and TNC and CD34+ counts. Greater than 40\u2003weeks\u2019 gestation predicted enhanced volume and TNC count. Cesarean section, two\u2010 versus one\u2010person collection, and not greater than 5\u2003minutes between placental delivery and collection produced superior volume. Increased TNC count was also seen in Caucasian women, primigravidae, female newborns, and collection duration of more than 5 minutes. A time between delivery of newborn and placenta of not greater than 10\u2003minutes predicted better volume and CD34+ count. By regression analysis, collection within not greater than 5\u2003minutes of placental delivery produced superior volume and TNC count.<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2002<\/jats:bold> Donor selection and collection technique modifications may improve product quality. TNC count appears to be more affected by different variables than CD34+ count.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2004.04117.x","type":"journal-article","created":{"date-parts":[[2005,1,19]],"date-time":"2005-01-19T14:28:27Z","timestamp":1106144907000},"page":"189-194","source":"Crossref","is-referenced-by-count":49,"title":["Impact of donor\u2010 and collection\u2010related variables on product quality in ex utero cord blood 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