{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:11:12Z","timestamp":1790946672361,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2004,9,22]],"date-time":"2004-09-22T00:00:00Z","timestamp":1095811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:p><jats:bold>BACKGROUND:\u2002<\/jats:bold> Donors are deferred for multiple reasons. Losses related to disease marker rates are well established. Donor and donation losses for other reasons, however, have not been extensively quantified.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:\u2002<\/jats:bold> To quantify these losses, three data sets from the Blood Centers of the Pacific were combined, permitting detailed analysis of year 2000 allogeneic whole\u2010blood donations.<\/jats:p><jats:p><jats:bold>RESULTS:\u2002<\/jats:bold> During 2000, 13.6\u2003percent of 116,165 persons who presented for donation were deferred at presentation. Short\u2010term deferral accounted for 68.5 percent (hematocrit was most common at 60%); long\u2010term deferral accounted for 21\u2003percent (travel to a malarial area and tattoo or other nonintravenous drug use needle exposure were most common at 59 and 29%, respectively); and multiple\u2010year or permanent deferral accounted for 10.5\u2003percent (UK travel [variant Creutzfeldt\u2010Jakob disease] risk and emigration from a malarial area were most common at 38 and 11%, respectively). Disease\u2010marker\u2010reactive donations represented 0.9\u2003percent of donor outcomes. The prevalence of deferral and also miscollection (under\u2010 and overweight units) varied by age, sex, and first\u2010time versus repeat donor status. Overall, miscollection led to a loss of 3.8\u2003percent of 100,141 collections, ranging from 1.9\u2003percent in repeat male donors 40 to 54 years of age to 10.7\u2003percent in first\u2010time female donors 16 to 24 years of age.<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2002<\/jats:bold> Loss of units from both first\u2010time and repeat donors due to temporary deferral and loss of units from miscollection are more common events than losses due to disease marker testing. Some of these losses may be avoidable and could increase the blood supply without having to recruit new donors.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2004.04160.x","type":"journal-article","created":{"date-parts":[[2004,9,22]],"date-time":"2004-09-22T09:53:43Z","timestamp":1095846823000},"page":"1417-1426","source":"Crossref","is-referenced-by-count":81,"title":["Quantifying losses to the donated blood supply due to donor deferral and miscollection"],"prefix":"10.1111","volume":"44","author":[{"given":"Brian","family":"Custer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean D.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom K.","family":"Hazlet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott D.","family":"Ramsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora V.","family":"Hirschler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward L.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Busch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,9,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1093\/ajhp\/57.22.2094","article-title":"Responsible use of blood products in response to supply and demand","volume":"57","author":"Colgan K","year":"2000","journal-title":"Am J Health Syst Pharm"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2002.00174.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890009002022"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41060751.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.2.229"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1998.38498257373.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41060730.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1001\/jama.1997.03540360035027","article-title":"Estimates of infectious disease risk factors in US blood donors. 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