{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T11:31:03Z","timestamp":1770895863324,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T00:00:00Z","timestamp":1128297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Reports of transfusion\u2010transmitted <jats:italic>Babesia microti<\/jats:italic> have risen steadily during the past several years, reflecting a concurrent increase in US cases of human babesiosis. Although several studies have measured <jats:italic>B.\u2003microti<\/jats:italic> antibodies in blood donors, little is known about associated parasitemia and the inherent risk of transmitting the parasite by transfusion.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:<\/jats:bold> Donations from blood donors located in <jats:italic>Babesia<\/jats:italic>\u2010endemic and nonendemic areas of Connecticut were tested for <jats:italic>B.\u2003microti<\/jats:italic> antibodies from July through September. Subsequently, an additional blood sample was collected from selected seropositive donors and tested by nested polymerase chain reaction (PCR) for <jats:italic>B.\u2003microti<\/jats:italic> nucleic acids.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> A total of 3490 donations, 1745 each from endemic and nonendemic areas, were tested for <jats:italic>B.\u2003microti<\/jats:italic> antibodies; 30 (0.9%) were confirmed as positive and seroprevalence rates peaked in July. Significantly more seropositive donations were from endemic areas (24, 1.4%) than nonendemic areas (6, 0.3%). Ten (53%) of 19 seropositive donors subsequently tested by PCR were positive.<\/jats:p><jats:p><jats:bold>CONCLUSION:<\/jats:bold>  <jats:italic>B.\u2003microti<\/jats:italic> seroprevalence was highest in those areas of Connecticut where the parasite is endemic. More than half of seropositive donors tested had demonstrable parasitemia, indicating that many are at risk for transmitting <jats:italic>B.\u2003microti<\/jats:italic> by blood transfusion. Three donors were identified as parasitemic in October, suggesting that donors may be at risk for transmitting the parasite outside of the peak period of community\u2010acquired infection.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2005.00609.x","type":"journal-article","created":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T09:24:55Z","timestamp":1128331495000},"page":"1804-1810","source":"Crossref","is-referenced-by-count":61,"title":["Demonstrable parasitemia among Connecticut blood donors with antibodies to <i>Babesia microti<\/i>"],"prefix":"10.1111","volume":"45","author":[{"given":"David A.","family":"Leiby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy P.S.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer E.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond 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