{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:18:12Z","timestamp":1771658292504,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,14]],"date-time":"2005-12-14T00:00:00Z","timestamp":1134518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p><jats:bold>BACKGROUND:\u2002<\/jats:bold> The high incidence of donor reactions in first\u2010time, 17\u2010year\u2010old Caucasian whole\u2010blood donors makes this group ideal for the study of donor reactions.<\/jats:p><jats:p><jats:bold>STUDY DESIGN and METHODS:\u2002<\/jats:bold> Donor reaction rates were retrospectively evaluated in 7274 first\u2010time, 17\u2010year\u2010old Caucasian whole\u2010blood donors based on observa\u2010tions recorded at the collection sites. The effect of sex and weight on donor reactions was determined. In addition, a model was developed to estimate how different blood collection volumes would affect donor reaction rates.<\/jats:p><jats:p><jats:bold>RESULTS:\u2002<\/jats:bold> The donor reaction rate was 12.0\u2003percent (870\/7274). Female donors overall had a higher donor reaction rate than male donors (16.7% vs. 7.3%) and also had a higher donor reaction rate than male donors at each 20\u2010lb weight interval in the range from 110 to 189\u2003lb. A model suggested that a change in the blood\u2010unit volume from 450 to 500\u2003mL would increase donor reaction rates by 18\u2003percent in either female or male donors, whereas a reduction in the blood\u2010unit volume from 500 to 400\u2003mL would decrease donor reaction rates by 29 and 27\u2003percent in female and male donors, respectively.<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2002<\/jats:bold> First\u2010time, 17\u2010year\u2010old Caucasian female donors had a higher donor reaction rate than male donors overall and at equivalent donor weights. In the range of present US blood\u2010unit volumes, a change in collection of as little as 50\u2003mL could have a significant impact on blood donor reaction rates in high\u2010school students.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2006.00713.x","type":"journal-article","created":{"date-parts":[[2005,12,14]],"date-time":"2005-12-14T14:57:00Z","timestamp":1134572220000},"page":"284-288","source":"Crossref","is-referenced-by-count":51,"title":["Donor reactions in high\u2010school donors: the effects of sex, weight, and collection volume"],"prefix":"10.1111","volume":"46","author":[{"given":"B.H.","family":"Newman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.L.","family":"Satz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.M.","family":"Janowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.A.","family":"Siegfried","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-7963(97)80011-9"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2003.00368.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1999.39399219291.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1980.20581034503.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1992.32192116426.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2002.00238.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2005.00212.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.23.6.901"},{"key":"e_1_2_5_10_2","first-page":"31S","article-title":"Comparison of donor reaction rates in high school, college, and general blood drives [abstract]","volume":"39","author":"Khan W","year":"1999","journal-title":"Transfusion"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-4825(03)00019-2"},{"key":"e_1_2_5_12_2","volume-title":"Epi Info, a database and statistics program for public health professionals","author":"Dean AG","year":"2002"},{"key":"e_1_2_5_13_2","first-page":"140A","article-title":"The effect of the blood donor's physical experience on blood donor return rates","volume":"43","author":"Newman B","year":"2003","journal-title":"Transfusion"},{"key":"e_1_2_5_14_2","first-page":"114","article-title":"The effect of blood donor syncopal reactions on subsequent blood donation [abstract]","volume":"39","author":"Cable R","year":"1999","journal-title":"Transfusion"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0041-1132.2004.371_1.x"},{"key":"e_1_2_5_16_2","first-page":"78A","article-title":"Effect of reaction in allogeneic whole\u2010blood donors on intervals from donation to next presentation [abstract]","volume":"44","author":"Siegfried B","year":"2004","journal-title":"Transfusion"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41121475.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2005.00595.x"},{"key":"e_1_2_5_19_2","first-page":"15S","article-title":"Whole blood collection volumes and donor safety: equivalence between 450 mL and 500 mL collections [abstract]","volume":"34","author":"Bianco C","year":"1994","journal-title":"Transfusion"},{"key":"e_1_2_5_20_2","first-page":"9","volume-title":"Standards for blood banks and transfusion services.","author":"Fridey JL","year":"2003"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2006.00713.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2006.00713.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T03:19:21Z","timestamp":1697253561000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2006.00713.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,14]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["10.1111\/j.1537-2995.2006.00713.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2006.00713.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12,14]]}}}