{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:23:34Z","timestamp":1791296614957,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,2,13]],"date-time":"2006-02-13T00:00:00Z","timestamp":1139788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold>BACKGROUND:\u2002<\/jats:bold> Bacterial contamination of platelet (PLT) components is an important cause of transfusion reactions. Recent efforts have focused on heightened surveillance to detect contamination before transfusion to limit recipient morbidity and mortality. Although identifying the cause of contamination is most often viewed in the context of recipient safety, this case illustrates the importance of a thorough evaluation on donor safety.<\/jats:p><jats:p><jats:bold>CASE REPORT:\u2002<\/jats:bold> A 68\u2010year\u2010old woman experienced a severe febrile reaction after a plateletpheresis transfusion. Blood cultures from the patient and from the plateletpheresis component were both positive for the presence of <jats:italic>Streptococcus agalactiae<\/jats:italic>. No abnormalities were identified on review of collection and processing records. The donor was asymptomatic and had a negative review of systems, a normal physical exam, normal laboratory values, and negative blood and urine cultures. One of three stool samples was positive for the presence of occult blood. Colonoscopy revealed a Dukes Stage\u2003B colonic adenocarcinoma. Fifteen months after surgical resection and adjuvant chemotherapy, the donor had no evidence of recurrent tumor.<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2002<\/jats:bold> Identification of bacteria in blood components should trigger a comprehensive donor evaluation, particularly if donor bacteremia is suspected. Organisms that may be associated with an enteric source should prompt a thorough gastrointestinal evaluation. Because the primary reservoir of <jats:italic>S.\u2003agalactiae<\/jats:italic> in the human body is the gastrointestinal tract, and because no findings suggested an alternate portal of entry in our male donor, a gastrointestinal source was suspected. In this case, an evaluation for organism\u2010specific pathology led to early identification of a potentially curable large bowel lesion.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2006.00760.x","type":"journal-article","created":{"date-parts":[[2006,2,13]],"date-time":"2006-02-13T09:22:10Z","timestamp":1139822530000},"page":"649-651","source":"Crossref","is-referenced-by-count":13,"title":["<i>Streptococcus agalactiae<\/i> sepsis after transfusion of a plateletpheresis concentrate: benefit of donor evaluation"],"prefix":"10.1111","volume":"46","author":[{"given":"Wesley\u2003T.","family":"Stevens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles\u2003D.","family":"Bolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime\u2003M.","family":"Oblitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David\u2003F.","family":"Stroncek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John\u2003E.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan\u2003F.","family":"Leitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,2,13]]},"reference":[{"key":"e_1_2_4_2_2","first-page":"424","volume-title":"Mandell, Douglas, and Bennett's principles and practice of infectious diseases.","author":"Edwards M","year":"2005"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17706-X"},{"key":"e_1_2_4_4_2","doi-asserted-by":"crossref","unstructured":"HillyerCD JosephsonCD BlajchmanMA et al.Bacterial contamination of blood components: risks strategies and regulation: joint ASH and AABB educational session in transfusion medicine.Hematology (Am Soc Hematol Educ Program)2003;575\u201089.","DOI":"10.1182\/asheducation-2003.1.575"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2001.41070857.x"},{"key":"e_1_2_4_6_2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.5858\/2004-128-279-BCOPUA","article-title":"Bacterial contamination of platelet units: a case report and literature survey with review of upcoming American Association of Blood Bank requirements","volume":"128","author":"Burns KH","year":"2004","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.1.195-204.2005"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021050"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3148.1998.00120.x"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0958-7578.2004.00506.x"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2004.00568.x"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-78-5-633"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66462-8"},{"key":"e_1_2_4_14_2","volume-title":"Standards for blood banks and transfusion services","year":"2004"},{"key":"e_1_2_4_15_2","volume-title":"Bacterial contamination of platelets: summary for clinicians on potential management issues related to transfusion recipients and blood donors","author":"AABB Bacterial Contamination Task Force.","year":"2005"},{"key":"e_1_2_4_16_2","first-page":"77","volume-title":"Mandell, Douglas, and Bennett's principles and practice of infectious diseases.","author":"Fowler VG","year":"2005"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2006.00760.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2006.00760.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T03:17:29Z","timestamp":1697253449000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2006.00760.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,13]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1111\/j.1537-2995.2006.00760.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2006.00760.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,13]]}}}