{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T12:07:58Z","timestamp":1772194078463,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T00:00:00Z","timestamp":1161907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Chimerism is the presence of two or more genetically distinct cell populations in one organism.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:<\/jats:bold> We report the identification of dispermic chimerism in a 19\u2010year\u2010old female volunteer blood donor. During routine ABO blood grouping strong reactions of the blood donors red blood cells (RBCs) with anti\u2010A reagents and mixed\u2010field reactions with anti\u2010B reagents were observed, while serum\u2010testing showed the absence of anti\u2010A and anti\u2010B antibodies. AB0 blood group genotyping, HLA\u2010typing and microsatellite analysis were performed using blood\u2010samples, buccal mucosa and fibroblasts of the blood\u2010donor and blood\u2010samples of her parents.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> AB0 blood group genotyping showed three ABO blood group alleles (0<jats:sup>1<\/jats:sup>, A<jats:sup>2<\/jats:sup> and B) in the DNA\u2010samples of the blood\u2010donor. The evidence of chimerism was supported by the detection of three alleles for the HLA\u2010A and HLA\u2010DRB1 loci. Microsatellite analysis with ten markers revealed three alleles for loci D7S821 and D19S412. All studies carried out, the third allele was always of paternal origin.<\/jats:p><jats:p><jats:bold>CONCLISION:<\/jats:bold> The results suggested a case of a human dispermic chimerism. Our proposed explanation for the development of chimerism in the reported case is the fertilization of an oocyte and the corresponding second polar body by two different sperms.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2006.01005.x","type":"journal-article","created":{"date-parts":[[2006,10,27]],"date-time":"2006-10-27T10:16:34Z","timestamp":1161944194000},"page":"1978-1981","source":"Crossref","is-referenced-by-count":19,"title":["Dispermic chimerism identified during blood group determination and HLA typing"],"prefix":"10.1111","volume":"46","author":[{"given":"Mira","family":"Mosebach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Parkner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sybille","family":"Jakubiczka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wieacker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcell U.","family":"Heim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,27]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4827.81"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2003.00515.x"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.13.6.528"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1980.tb05991.x"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V70.5.1331.1331"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/bbmt.2001.v7.pm11669214"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199801153380305"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-313X.1981.tb00749.x"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013452"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050543"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1983.tb03657.x"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050543"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/301796"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1537-2995.2006.01005.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1537-2995.2006.01005.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T03:29:57Z","timestamp":1695958197000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1537-2995.2006.01005.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,27]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1537-2995.2006.01005.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1537-2995.2006.01005.x","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,27]]}}}