{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:12:04Z","timestamp":1761487924928},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,9,27]],"date-time":"2007-09-27T00:00:00Z","timestamp":1190851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> A recently published study has reported that donor\u2010recipient Rhesus (Rh)\u2010mismatched allogeneic hematopoietic stem cell transplantation independently led to significantly poorer survival. This suggests that donor\u2010recipient Rh mismatching is a risk factor in allogeneic hematopoietic stem cell transplantation and should be a criterion for donor selection.<\/jats:p><jats:p><jats:bold>STUDY DESIGN AND METHODS:<\/jats:bold> To further evaluate this issue, 258 consecutive patients who underwent myeloablative or submyeloablative allogeneic hematopoietic stem cell transplantation at our institution were analyzed to determine the association between the Rh mismatch pattern and 5\u2010year actuarial survival. Secondary endpoints analyzed were the association of donor\u2010recipient Rh mismatch and event\u2010free survival, transplant\u2010related mortality, incidence of acute graft\u2010versus\u2010host disease (GVHD), and incidence of chronic GVHD.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> In our analysis, there were no significant associations between donor\u2010recipient Rh mismatch pattern and overall survival, event\u2010free survival, transplant\u2010related mortality, incidence of acute GVHD, or incidence of chronic GVHD. On multivariate Cox proportional hazard analyses, the donor\u2010recipient Rh mismatch pattern was not independently predictive of overall survival.<\/jats:p><jats:p><jats:bold>CONCLUSION:<\/jats:bold> Donor\u2010recipient Rh mismatch is not a risk factor in allogeneic hematopoietic stem cell transplantation and does not affect transplant outcomes.<\/jats:p>","DOI":"10.1111\/j.1537-2995.2007.01501.x","type":"journal-article","created":{"date-parts":[[2007,9,27]],"date-time":"2007-09-27T22:57:17Z","timestamp":1190933837000},"page":"163-168","source":"Crossref","is-referenced-by-count":11,"title":["Lack of effect of donor\u2010recipient Rh mismatch on outcomes after allogeneic hematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"48","author":[{"given":"Baldeep","family":"Wirk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas 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